Evidence map›Paper›PMID 39952958›Full record

ArticleNPJ vaccines2025

LmCen

Thouraya Boussoffara, Imen Labidi, Malek Trimèche, Ifhem Chelbi, Khalil Dachraoui, Nourhane Msallem, Mohammed Abdo Saghir Abbas, Saifedine Cherni, Kamaleshwar P Singh, Swarnendu Kaviraj and 14 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in NPJ vaccines, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors.

Thouraya BoussoffaraLaboratory of Transmission, Control, and Immunobiology of Infections. Pasteur Institute of Tunis. University of Tunis El Manar, Tunis, Tunisia.
Imen LabidiUnit of Vector Ecology, Pasteur Institute of Tunis, Tunis, Tunisia.
Malek TrimècheLaboratory of Transmission, Control, and Immunobiology of Infections. Pasteur Institute of Tunis. University of Tunis El Manar, Tunis, Tunisia.
Ifhem ChelbiLaboratory of Transmission, Control, and Immunobiology of Infections. Pasteur Institute of Tunis. University of Tunis El Manar, Tunis, Tunisia.
Khalil DachraouiLaboratory of Transmission, Control, and Immunobiology of Infections. Pasteur Institute of Tunis. University of Tunis El Manar, Tunis, Tunisia.
Nourhane MsallemUnit of Vector Ecology, Pasteur Institute of Tunis, Tunis, Tunisia.
Mohammed Abdo Saghir AbbasLaboratory of Transmission, Control, and Immunobiology of Infections. Pasteur Institute of Tunis. University of Tunis El Manar, Tunis, Tunisia.
Saifedine CherniLaboratory of Transmission, Control, and Immunobiology of Infections. Pasteur Institute of Tunis. University of Tunis El Manar, Tunis, Tunisia.
Kamaleshwar P SinghGennova Biopharmaceuticals Limited, Hinjewadi Phase II, Pune, Maharashtra, India.
Swarnendu KavirajGennova Biopharmaceuticals Limited, Hinjewadi Phase II, Pune, Maharashtra, India.
Ranadhir DeyDivision of Emerging and Transfusion Transmitted Diseases, Office of Blood Research and Review, Center for Biologics Evaluation and Research, Food and Drug Administration, Silver Spring, MD, USA.ORCID http://orcid.org/0000-0003-0069-7867
Sanjay VarikutiThe Ohio State University, Columbus, Ohio, USA.
Sreenivas GannavaramDivision of Emerging and Transfusion Transmitted Diseases, Office of Blood Research and Review, Center for Biologics Evaluation and Research, Food and Drug Administration, Silver Spring, MD, USA.ORCID http://orcid.org/0000-0002-6557-8220
Lais da S PereiraDivision of Emerging and Transfusion Transmitted Diseases, Office of Blood Research and Review, Center for Biologics Evaluation and Research, Food and Drug Administration, Silver Spring, MD, USA.
Wen-Wei ZhangDepartment of Microbiology and Immunology, McGill University, Montreal, QC, Canada.ORCID http://orcid.org/0000-0003-1996-876X
Patrick LypaczewskiDepartment of Microbiology and Immunology, McGill University, Montreal, QC, Canada.ORCID http://orcid.org/0000-0002-5550-712X
Shinjiro HamanoDepartment of Parasitology, Institute of Tropical Medicine (NEKKEN), The Joint Usage/Research Center on Tropical Disease, Nagasaki University, Nagasaki, Japan.ORCID http://orcid.org/0000-0003-3881-8337
Hirotomo KatoDivision of Medical Zoology, Department of Infection and Immunity, Jichi Medical University, Tochigi, Japan.
Sanjay SinghGennova Biopharmaceuticals Limited, Hinjewadi Phase II, Pune, Maharashtra, India.
Hechmi LouzirLaboratory of Transmission, Control, and Immunobiology of Infections. Pasteur Institute of Tunis. University of Tunis El Manar, Tunis, Tunisia.
Hira L NakhasiDivision of Emerging and Transfusion Transmitted Diseases, Office of Blood Research and Review, Center for Biologics Evaluation and Research, Food and Drug Administration, Silver Spring, MD, USA.ORCID http://orcid.org/0000-0003-4941-1620
Abhay R SatoskarThe Ohio State University, Columbus, Ohio, USA.ORCID http://orcid.org/0000-0001-5989-1520
Greg MatlashewskiDepartment of Microbiology and Immunology, McGill University, Montreal, QC, Canada.ORCID http://orcid.org/0000-0002-8971-5525
Elyes ZhiouaLaboratory of Transmission, Control, and Immunobiology of Infections. Pasteur Institute of Tunis. University of Tunis El Manar, Tunis, Tunisia. elyes.zhioua@gmail.com.

Funding

Wellcome TrustWellcome Trust (Wellcome) 209336/Z/17/Z
6 · The paper itself

Abstract

Dogs are the main reservoir host of Leishmania infantum, etiological agent of zoonotic visceral leishmaniasis (ZVL). An effective vaccine against Canine Visceral Leishmaniasis (CVL) will help the control and elimination of ZVL. In this study, we evaluated in dogs the safety, immunogenicity, and efficacy of a live attenuated Leishmania major Centrin gene-deleted (LmCen

Identifiers

PMID39952958
PMCPMC11828870

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.