ArticleEnvironmental research2025
Ambient temperature in relation to ovarian reserve and early outcomes following ovarian stimulation and in vitro fertilization.
Article in Environmental research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The effects of heat stress on the ovary, follicles, and oocytes: a systematic review†.Biology of reproduction · 2025Pooled it
- The association between heat waves and pregnancy outcome among women undergoing assisted reproductive technology in Sichuan, China.BMC public health · 2026Article
- Association between ambient temperature exposure and pregnancy outcomes in participants undergoing IVF: a retrospective cohort study.Journal of assisted reproduction and genetics · 2026Article
- The impact of season, temperature, and direct normal irradiance on IVF pregnancy outcomes: a retrospective cohort study.International journal of biometeorology · 2025Article
- A retrospective study on the association of ambient air pollutants and temperature co-exposure with female infertility risk in Chengdu, China.Scientific reports · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
Abstract
introductionThere is limited epidemiologic evidence on the associations between ambient temperature and early outcomes of in vitro fertilization (IVF). This study examined the association between ambient temperature exposures during spermatogenesis in males and folliculogenesis in females with early IVF outcomes.
methodsThis retrospective cohort study included 529 oocyte donors linked to male partners of 1154 recipient couples who underwent 1379 oocyte thaw cycles between 2008 and 2020 at an IVF clinic in Atlanta, Georgia, USA. Daily ambient mean (T
resultsHigher ambient temperature exposures during folliculogenesis and ovarian stimulation generally had negative, though imprecise, associations with oocyte yield (% change in total oocytes retrieved per IQR increase in mean temperature = -6.9% 95% CI -18.5,6.3). Higher temperature exposures during folliculogenesis (aOR = 1.85 95% CI 1.16, 2.95) and ovarian stimulation (aOR = 2.14 95% CI 1.44, 3.19) were associated with higher oocyte survival and higher T
conclusionsHigher ambient temperature exposure during follicular development was positively associated with oocyte survival and fertilization. These findings highlight the reproductive health implications of increasing global average temperatures, though more research is needed to clarify these associations.
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Registered trials
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