Evidence map›Paper›PMID 39951764›Full record

ArticleOptics letters2025

Wide-field self-referenced optical coherence tomography imaging of the corneal microlayers.

Marco Ruggeri, Francesco Pozzo Giuffrida, Ngoc Lan Vy Truong, Jean-Marie Parel, Florence Cabot, Mohamed Abou Shousha, Fabrice Manns, Arthur Ho

Abstract read
In one paragraph

Article in Optics letters, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Marco Ruggeri
Francesco Pozzo Giuffrida
Ngoc Lan Vy Truong
Jean-Marie Parel
Florence Cabot
Mohamed Abou Shousha
Fabrice Manns
Arthur Ho

Funding

Research Programming ModuleP30EY007551 · NEI · UNIVERSITY OF HOUSTON · PI Nimesh Bhikhu Patel · 1988 to 2026
$16.4M
Wide-field corneal microlayer tomography for keratoconusR01EY033429 · NEI · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI Mohamed Fadel Abou Shousha, Marco Ruggeri · 2022 to 2026
$2.0M
NEI NIH HHS P30 EY007551NEI NIH HHS R01 EY033429
6 · The paper itself

Abstract

We present a technique for wide-field OCT imaging of the cornea using self-referenced interference of the anterior corneal surface with the underlying corneal structure. The method employs a custom objective lens that ensures that the probing beam remains nearly perpendicular to the anterior corneal surface, effectively utilizing it as a reference to generate interference. This approach allows for high-resolution, three-dimensional imaging of corneal layers over a 9mm optical zone. Tests on human subjects show the ability of the system to quantify the anterior corneal layer thickness.

Identifiers

PMID39951764
PMCPMC12691542

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.