Evidence map›Paper›PMID 39951449›Full record

ArticlePloS one2025

Association between anthropometric indices and chronic kidney disease: Insights from NHANES 2009-2018.

Xinyun Chen, Zheng Wu, Xingyu Hou, Wenhui Yu, Chang Gao, Shenju Gou, Ping Fu

Abstract read
In one paragraph

Article in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Xinyun ChenDepartment of Nephrology, Kidney Research Institutes, West China Hospital, Sichuan University, Chengdu, China.
Zheng WuBusiness School, Sichuan University, Chengdu, China.ORCID 0000-0002-9251-621X
Xingyu HouSchool of Economics and Management, North China Electric Power University, Beijing, China.
Wenhui YuDepartment of Nephrology, Kidney Research Institutes, West China Hospital, Sichuan University, Chengdu, China.
Chang GaoDepartment of Nephrology, Kidney Research Institutes, West China Hospital, Sichuan University, Chengdu, China.
Shenju GouDepartment of Nephrology, Kidney Research Institutes, West China Hospital, Sichuan University, Chengdu, China.ORCID 0000-0002-0151-5036
Ping FuDepartment of Nephrology, Kidney Research Institutes, West China Hospital, Sichuan University, Chengdu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe strong association between obesity and chronic kidney disease (CKD) has been empirically validated, yet traditional measures like the Body Mass Index (BMI) fail to accurately assess the extent of obesity due to CKD's characteristics, such as reduced muscle mass and increased visceral fat. This study investigates the association between CKD and several anthropometric indices, including A Body Shape Index (ABSI), Body Roundness Index (BRI), Waist-to-Height Ratio (WHtR), and the Conicity Index (C-index), to determine their predictive capabilities.

methodsBased on the datasets from the National Health and Nutrition Examination Survey (NHANES) 2009-2018, weighted multivariable regression analyses were carried out to examine the independent relationship between two anthropometric indices and CKD. Also, subgroup analyses, restricted cubic spline regression (RCS), and receiver operating characteristic curve analysis were conducted for further data analyses.

resultsA total of 24,162 participants were enrolled in this study. After adjusting for confounding factors, ABSI, BRI, WHtR, and the C-index were significantly associated with an increased risk of CKD, while BMI was not. Height showed a protective effect against CKD. ABSI and the C-index demonstrated the highest areas under the curve (AUCs), indicating superior predictive capabilities compared to traditional measures like BMI and waist circumference (WC). Subgroup analyses revealed significant interactions between the anthropometric indices and factors such as age, disease status, dietary intake, and physical activity levels.

conclusionsThis study highlights the significant associations between various anthropometric indices (including ABSI, BRI, WHtR, and C-index) and the risk of CKD. ABSI and the C-index demonstrated the strongest predictive capabilities for CKD, with the highest AUC values.

Indexed as

AnthropometryObesityRenal Insufficiency, ChronicAdultAgedBody Mass IndexFemaleHumansMaleMiddle AgedNutrition SurveysRisk FactorsROC CurveWaist CircumferenceWaist-Height Ratio

Identifiers

PMID39951449
PMCPMC11828394

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.