Evidence map›Paper›PMID 39951441›Full record

ArticlePloS one2025

Cost profiles of cancer patients at the end of life: Estimates from the EPICOST-study.

Stefano Guzzinati, Alessandra Andreotti, Tania Lopez, Silvia Gori, Alberto Gagliani, Sandra Mallone, Daniela Pierannunzio, Andrea Tavilla, Alessandra Buja, Manuel Zorzi and 1 more

Abstract read
In one paragraph

Article in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Stefano GuzzinatiVeneto Cancer Registry, Epidemiological Department, Azienda Zero, Padova, Italy.ORCID 0000-0002-4908-5506
Alessandra AndreottiVeneto Cancer Registry, Epidemiological Department, Azienda Zero, Padova, Italy.ORCID 0009-0003-6528-5713
Tania LopezNational Centre for Disease Prevention and Health Promotion, National Institute of Health, Rome, Italy.
Silvia GoriImmunology and Diagnostic Molecular Oncology Unit, Veneto Institute of Oncology IOV-IRCCS, Padua, Italy.ORCID 0000-0002-8528-0608
Alberto GaglianiDepartment of Cardiological, Thoracic and Vascular Sciences and Public Health, University of Padua, Padua, Italy.
Sandra MalloneNational Centre for Disease Prevention and Health Promotion, National Institute of Health, Rome, Italy.
Daniela PierannunzioNational Centre for Disease Prevention and Health Promotion, National Institute of Health, Rome, Italy.
Andrea TavillaNational Centre for Disease Prevention and Health Promotion, National Institute of Health, Rome, Italy.
Alessandra BujaDepartment of Cardiological, Thoracic and Vascular Sciences and Public Health, University of Padua, Padua, Italy.
Manuel ZorziVeneto Cancer Registry, Epidemiological Department, Azienda Zero, Padova, Italy.
Silvia FrancisciNational Centre for Disease Prevention and Health Promotion, National Institute of Health, Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe study aims to analyze care and cost patterns in the Veneto region for cancer patients in the final phase of their disease.

methodsThe study cohort includes adult patients alive on 1.1.2018, which have been diagnosed with cancer at the age 15+ in a 28-years period, spanning from 1990 to 2017, and died within 12 months from prevalence date. The end-of-life (EOL) prevalent cases included in the study cohort are identified by the Veneto Tumor Registry. Primary tumors considered in the analysis are colon, rectum, skin melanoma, female breast, thyroid. Patient monthly average EOL costs, patient annual average EOL costs and total regional costs have been estimated separately for each cancer site/sex/age group/health care service database.

resultsThe estimated EOL total cost, for the five analyzed cancer types in the Veneto Region, is approximately 53 million euros. Costs associated with cancer treatment tend to increase in the final phase of the disease. In general, Hospital Admission is the main driver cost in all types of cancer considered, with the only exception in melanoma, where Hospital Drugs features the highest contribution. Moreover, costs differ significantly depending on the type of cancer, gender, and age, revealing highest average costs associated with younger patients.

conclusionsThis study provides a comprehensive analysis of healthcare budget distribution in the last year of life, enabling healthcare planners to predict cancer burden in the future. This model can be applied to other Italian regions and countries with different healthcare systems.

Indexed as

Health Care CostsNeoplasmsTerminal CareAdolescentAdultAgedAged, 80 and overCohort StudiesFemaleHumansItalyMaleMiddle AgedRegistriesYoung Adult

Identifiers

PMID39951441
PMCPMC11828425

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.