Trial reportArchives of dermatological research2025
Assessment of clinical efficacy in melasma treatment with picosecond laser combined with Shumin Star.
Trial report in Archives of dermatological research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
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Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study aimed to evaluate the clinical efficacy of picosecond laser therapy combined with the Shumin Star in treating melasma and to explore the role of skin barrier function indicators in the assessment of this treatment process. Ninety patients with melasma were randomly divided into a study group and a control group. The study group received picosecond laser therapy combined with the Shumin Star, while the control group received only picosecond laser therapy. The clinical efficacy and adverse reactions of both groups were compared. Changes in skin barrier function before and after treatment were observed. The receiver operating characteristic (ROC) curve analysis was used to evaluate the predictive value of skin barrier function for treatment outcomes. The clinical efficacy of the study group was significantly superior to that of the control group (95.56% versus 82.22%, P = 0.044). After 3 months of treatment, the study group showed significant improvements of skin barrier function in TEWL, stratum corneum hydration, and sebum content, with a significantly lower MASI total score compared to the control group. During the treatment course, the incidence of adverse reactions in the study group was lower than that in the control group. Picosecond laser therapy combined with the Shumin Star is effective in treating melasma. Skin barrier function can be used to assess the clinical efficacy of this treatment, providing valuable reference values for clinical application and promotion.
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Identifiers
39951164What OpenQuestion holds
Registered trials
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