Evidence map›Paper›PMID 39951114›Full record

ReviewNaunyn-Schmiedeberg's archives of pharmacology2025

Research progress of TRPV4 in pain over the past 20 years: a bibliometric analysis.

Lele Huang, Qiwen Xuan, Ying Li, Jinghui Huang, Fanfu Fang

Abstract readReview
PubMed Publisher
In one paragraph

Review in Naunyn-Schmiedeberg's archives of pharmacology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Lele Huang *Department of Sports Medicine, Peking University Third Hospital, Institute of Sports Medicine of Peking University, Beijing, China.
Qiwen Xuan *School of Traditional Chinese Medicine, Naval Medical University, Shanghai, China.
Ying LiDepartment of Rehabilitation Medicine, The First Affiliated Hospital of the Naval Medical University,, No. 168 Changhai Road, Yangpu District, Shanghai, China. 1179892653@qq.com.
Jinghui HuangDepartment of Rehabilitation Medicine, The First Affiliated Hospital of the Naval Medical University,, No. 168 Changhai Road, Yangpu District, Shanghai, China. huangran_1234@163.com.
Fanfu FangDepartment of Rehabilitation Medicine, The First Affiliated Hospital of the Naval Medical University,, No. 168 Changhai Road, Yangpu District, Shanghai, China. fangfanfu@126.com.

Funding

Military high-level scientific and technological Innovation personnel project (Project Number (2020) QN06128)Shanghai Shenkang Hospital Development Center to promote municipal hospital clinical skills and clinical innovation ability three-year action plan project SHDC2022CRD004
6 · The paper itself

Abstract

This study aims to explore the research hotspots and future research trends of transient receptor potential vanilloid 4 (TRPV4) in pain over the past two decades, with the objective of gaining insight into the development direction and focus of this field. A total of 791 articles were included in this study by searching the Web of Science Core Collection (WOSCC) database. To enhance research quality and accuracy, keywords with similar meanings were combined to eliminate ambiguity. Data visualization analysis was conducted using CiteSpace and VOSviewer, encompassing the examination of countries, research institutions, authors, journals, keywords, references, and categories. Over the past 20 years, 791 scientific articles on TRPV4 and pain have been reviewed, originating from 52 countries, involving 885 research units, 4121 authors, and published in 332 journals. The United States, China, and Japan emerged as core contributors in this field. Prominent research institutions include Duke University (United States) and the University of California, San Francisco (United States). The most prolific researchers include Liedtke, Wolfgang (United States), Bunnett, Nigel W. (United States), and Yue, Shou-wei (China). Research on TRPV4 and pain predominantly focuses on the molecular mechanisms, role of pain models, drug development, and clinical applications, aimed at advancing pain treatment. This study provides a comprehensive overview of the literature on TRPV4 and pain over the past two decades, offering researchers and scholars fresh insights into the field's development trends and future directions.

Indexed as

Biomedical ResearchPainTRPV Cation ChannelsAnimalsBibliometricsHumansTRPV4 protein, humanTRPV Cation ChannelsBibliometric analysisCiteSpacePainTRPV4VOSviewer

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.