Evidence map›Paper›PMID 39951097›Full record

ArticleThe Pediatric infectious disease journal2025

Knowledge About Respiratory Syncytial Virus and Acceptance of Infant Monoclonal Antibody for RSV and RSV Vaccination During Pregnancy.

Jennifer L Kuntz, Tara M Babu, Leora R Feldstein, Janet A Englund, Collrane J Frivold, Holly C Groom, Ning Smith, Alexandra M Varga, Sarah N Cox, Stephen P Fortmann and 12 more

Abstract read
In one paragraph

Article in The Pediatric infectious disease journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Jennifer L KuntzFrom the Kaiser Permanente Center for Health Research, Portland, Oregon.ORCID 0000-0002-0017-6853
Tara M BabuDepartment of Medicine, University of Washington, Seattle, Washington.
Leora R FeldsteinCoronavirus and Other Viral Respiratory Diseases Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia.
Janet A EnglundSeattle Children's Research Institute, Seattle, Washington.
Collrane J FrivoldDepartment of Medicine, University of Washington, Seattle, Washington.
Holly C GroomFrom the Kaiser Permanente Center for Health Research, Portland, Oregon.
Ning SmithFrom the Kaiser Permanente Center for Health Research, Portland, Oregon.
Alexandra M VargaFrom the Kaiser Permanente Center for Health Research, Portland, Oregon.
Sarah N CoxDepartment of Medicine, University of Washington, Seattle, Washington.
Stephen P FortmannFrom the Kaiser Permanente Center for Health Research, Portland, Oregon.
Richard A MularskiFrom the Kaiser Permanente Center for Health Research, Portland, Oregon.
Mark A SchmidtFrom the Kaiser Permanente Center for Health Research, Portland, Oregon.
Ana A WeilDepartment of Medicine, University of Washington, Seattle, Washington.
Cassandra L BoisvertFrom the Kaiser Permanente Center for Health Research, Portland, Oregon.
Madison HollcroftDepartment of Medicine, University of Washington, Seattle, Washington.
Tara L HatchieDepartment of Medicine, University of Washington, Seattle, Washington.
Natalie LoDepartment of Medicine, University of Washington, Seattle, Washington.
Melissa P MacMillanDepartment of Medicine, University of Washington, Seattle, Washington.
Sacha ReichFrom the Kaiser Permanente Center for Health Research, Portland, Oregon.
Neil YetzFrom the Kaiser Permanente Center for Health Research, Portland, Oregon.
Helen Y ChuDepartment of Medicine, University of Washington, Seattle, Washington.
Allison L NalewayFrom the Kaiser Permanente Center for Health Research, Portland, Oregon.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRespiratory syncytial virus (RSV) is the leading cause of hospitalization among infants in the United States (US). RSV immunization, in the form of a monoclonal antibody (mAb) for infants and vaccines for pregnant people, may reduce infant RSV risk.

methodsIn April and May 2023, we surveyed adults with children in Oregon and Washington about the likelihood to accept infant mAb and maternal RSV vaccine and RSV awareness. We used multivariable logistic regression to identify predictors of self-reported likelihood of accepting RSV immunization.

resultsAmong 1082 respondents, 68% and 70% responded they would very likely accept infant mAb or maternal RSV vaccine, respectively. Respondents had lower odds of accepting infant mAb (OR: 0.10, 95% CI: 0.07-0.15) and maternal RSV vaccine (OR: 0.16, 95% CI: 0.12-0.23) if they were somewhat or very concerned about side effects. Respondents had higher odds of accepting infant mAb if they received an influenza vaccination (OR: 3.79, 95% CI: 1.88-7.63). Respondents had higher odds of accepting maternal vaccine if they had an advanced degree (OR: 1.70, 95% CI: 1.06-2.73), had received an influenza vaccination (OR: 3.62, 95% CI: 1.80-7.25), or were aware of RSV before our survey (OR: 2.03, 95% CI: 1.03-4.01).

conclusionMost respondents reported that they would likely accept RSV mAb for their infant or an RSV vaccine during pregnancy. Concerns about side effects lowered the odds of accepting immunization, however, nearly one-half of those concerned about side effects still expressed a high likelihood of accepting either immunization.

Indexed as

Antibodies, MonoclonalHealth Knowledge, Attitudes, PracticePatient Acceptance of Health CarePregnancy Complications, InfectiousRespiratory Syncytial Virus, HumanRespiratory Syncytial Virus InfectionsRespiratory Syncytial Virus VaccinesVaccinationAdultFemaleHumansInfantMaleOregonPregnancySurveys and QuestionnairesAntibodies, MonoclonalRespiratory Syncytial Virus Vaccines

Identifiers

PMID39951097
PMCPMC13446117

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.