Evidence map›Paper›PMID 39951010›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2025

Tailoring Piezoelectric Nanogenerators and Microdevices for Cellular Excitation: Impact of Size and Morphology.

Laura Lefaix, Marc Navarro, Carme Nogués, Andreu Blanquer, Gonzalo Murillo

Abstract read
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Laura LefaixInstitute of Microelectronics of Barcelona (IMB-CNM, CSIC), Barcelona, 08193, Spain.ORCID https://orcid.org/0000-0002-9056-1041
Marc NavarroInstitute of Microelectronics of Barcelona (IMB-CNM, CSIC), Barcelona, 08193, Spain.ORCID https://orcid.org/0000-0002-4917-7929
Carme NoguésUniversitat Autònoma de Barcelona, Bellaterra, Barcelona, 08193, Spain.
Andreu BlanquerUniversitat Autònoma de Barcelona, Bellaterra, Barcelona, 08193, Spain.
Gonzalo MurilloInstitute of Microelectronics of Barcelona (IMB-CNM, CSIC), Barcelona, 08193, Spain.ORCID https://orcid.org/0000-0002-0368-1900

Funding

European Union EUR2020-112082Generalitat de Catalunya-AGAUR 2021-SGR-00122Generalitat de Catalunya-AGAUR 2021 SGR 00497Horizon 2020 program of research and innovation of the European Union 801370Junior Leader Retaining Fellowship program 11700010Ramon y Cajal Fellowship RYC2020-030501-ISpanish Government PID2020-116844RB-C21Spanish Government PID2020-119350RA-I00Spanish Government PID2023-148047OA-C22Spanish Government PID2023-148047OB-C21
6 · The paper itself

Abstract

The use of piezoelectric devices as wireless electrical stimulators is an emerging research topic. In this study, piezoelectric microdevices, consisting of ZnO nanosheets (NSs) functioning as piezoelectric nanogenerators (NGs) grown on top of silicon microparticles, to electrically stimulate cell are designed. The morphology of the ZnO NSs is optimized by tuning the thickness of the aluminum nitride (AlN) catalyst layer and adjusting the growth duration. ZnO NSs grown on thinner AlN layers (≤ 200 nm) and subjected to 9 h of hydrothermal growth exhibit the most suitable characteristics for cell stimulation, balancing crystal size, and electric field generation. The generation of a local electric field capable of exciting osteoblast cells is inferred from finite element simulations and intracellular calcium influx measurements. The internalization rate of silicon microdevices of varying sizes (3 × 3, 6 × 10, 12 × 18 µm

Indexed as

Electric StimulationNanotechnologyOsteoblastsCell Line, TumorHumansZinc OxideZinc Oxidebioelectronicscell stimulationmicrodevicenanogeneratorspiezoelectrics

Identifiers

PMID39951010
PMCPMC12199572

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.