ArticleRadiology. Imaging cancer2025
Clinical and Imaging Predictors of False-Positive and False-Negative Results in Prostate Multiparametric MRI Using PI-RADS Version 2.
Article in Radiology. Imaging cancer, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- From signal-intensity ratio to decision-grade triage in prostate MRI.Abdominal radiology (New York) · 2026Article
- Value of T2-weighted signal intensity index in reducing unnecessary biopsies for peripheral zone lesions PI-RADS (v2.1) ≥ 3.Abdominal radiology (New York) · 2026Article
- Clinical utility of the prostate health index density in patients with negative mpMRI or prior negative biopsy.Prostate international · 2026Article
- Accuracy of Diagnosis and Anticipation of Future Treatment in Pediatric Peripelvic Infections: The Role of Multisurgeon Review and Implications for Future Machine Learning Algorithms.Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews · 2026Article
- Predictive factors for negative prostate biopsy in PI-RADS 5 patients: a multivariate analysis of clinical and imaging-based factors.World journal of urology · 2026Article
- Biparametric magnetic resonance imaging-based radiomics model can improve the detection of dense and sparse prostate cancers.Quantitative imaging in medicine and surgery · 2025Article
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Authors and funding
9 authors.
Funding
Abstract
Purpose To evaluate predictors of false-positive (FP) and false-negative (FN) results for prostate cancer at prostate multiparametric MRI (mpMRI) using the Prostate Imaging and Reporting Data System version 2 (PI-RADS v2). Materials and Methods This was a single-center retrospective cohort study of 2548 consecutive patients who underwent prostate mpMRI examinations (October 2016-July 2022) containing zero or one PI-RADS v2 category 3-5 lesions. Prostate mpMRI examinations were interpreted by 13 radiologists. FP results were defined as prospective PI-RADS v2 score of 3 or higher but benign or grade group 1 prostate cancer at subsequent combined targeted and systematic biopsy. FN results were defined as prospective PI-RADS v2 score 2 or lower but grade group 2 or higher prostate cancer at subsequent combined targeted and systematic biopsy. Predictors of FP and FN results were assessed by logistic regression. Results Among the 2548 patients (mean age, 65.7 years ± 7.6 [SD]; all male) analyzed, 52.0% (831 of 1597) had FP results and 15.8% (150 of 951) had FN results at mpMRI. FP results were more likely for younger patients (odds ratio [OR], 0.95/y;
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