Evidence map›Paper›PMID 39950847›Full record

ReviewVirulence2025

Role of non-coding RNAs in the pathogenesis of viral myocarditis.

Zhijuan Kang, Liang Zhang, Zuocheng Yang

Abstract readReview
In one paragraph

Review in Virulence, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
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  3. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Zhijuan KangDepartment of Nephrology, Rheumatology and Immunology, The Affiliated Children's Hospital of Xiangya School of Medicine, Central South University (Hunan children's hospital), Changsha, Hunan, China.
Liang ZhangDepartment of Nephrology, Rheumatology and Immunology, The Affiliated Children's Hospital of Xiangya School of Medicine, Central South University (Hunan children's hospital), Changsha, Hunan, China.
Zuocheng YangDepartment of Pediatrics, Third Xiangya Hospital of Central South University, Changsha, Hunan, China.ORCID 0000-0003-0088-7564

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Viral myocarditis (VMC) is a common inflammatory disease of the myocardium that is characterized mainly by inflammatory cell infiltration and cardiomyocyte necrosis. Coxsackievirus B3 (CVB3) is a common cause of VMC, although major progress has been made in the treatment of VMC, the long-term prognosis is still not ideal and further research is needed. Non-coding RNAs (ncRNAs) are RNA molecules without coding functions and include microRNAs (miRNAs), long non-coding RNAs (lncRNAs) and circular RNAs (circRNAs), which play extensive regulatory roles in gene expression; however, their mechanisms of action in CVB3-induced VMC remain incompletely understood. Here, we review the currently known roles of various ncRNAs in CVB3-induced VMC models, with a focus on cell death, inflammation and viral replication, with the aim of providing a reference for their therapeutic or vaccine development for the treatment of VMC.

Indexed as

Coxsackievirus InfectionsEnterovirus B, HumanMyocarditisRNA, UntranslatedAnimalsHumansMicroRNAsRNA, CircularRNA, Long NoncodingVirus ReplicationMicroRNAsRNA, CircularRNA, Long NoncodingRNA, Untranslatedcell deathcoxsackievirus B3inflammationnon-coding RNAsviral myocarditisviral replication

Identifiers

PMID39950847
PMCPMC11849450

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.