Evidence map›Paper›PMID 39950548›Full record

ArticleVeterinary medicine and science2025

Imaging and Pathological Comprehensive Analysis of Oesophageal Squamous Cell Carcinoma in a Rhesus Monkey (Macaca mulatta).

Heling Li, Lixian Chen, Long Zhang, Xinglong Chen, Hong Wang

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Veterinary medicine and science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Heling LiState Key Laboratory of Primate Biomedical Research, Institute of Primate Translational Medicine, Kunming University of Science and Technology, Kunming, Yunnan, China.
Lixian ChenKunming Biomed International Ltd., Kunming, Yunnan, China.
Long ZhangKunming Biomed International Ltd., Kunming, Yunnan, China.
Xinglong ChenState Key Laboratory of Primate Biomedical Research, Institute of Primate Translational Medicine, Kunming University of Science and Technology, Kunming, Yunnan, China.
Hong WangState Key Laboratory of Primate Biomedical Research, Institute of Primate Translational Medicine, Kunming University of Science and Technology, Kunming, Yunnan, China.ORCID 0009-0004-6763-3168

Funding

Natural Science Foundation of Yunnan Province 202001BC070001 202102AA100053
6 · The paper itself

Abstract

Squamous cell carcinoma (SCC) has a high incidence in non-human primates (NHPs), which affects animal health and causes huge losses to the experimental monkey breeding industry. In this case, gastroscope showed a smooth-surfaced elevated lesion located approximately 18 cm from the incisor teeth of the diseased rhesus monkey. Computed tomography (CT) showed a space-occupying lesion in the oesophagus. Haematoxylin & eosin (HE) staining revealed an invasive tumour of polygonal nests in the submucosa and muscularis, while keratosis and nuclear atypia were also observed. Immunohistochemistry (IHC) studies revealed tumour cells positive for p63, CK5/6, p40, CK20, CK7 and CK19. Based on imaging and pathology findings, the rhesus monkey was diagnosed as oesophageal squamous cell carcinoma (ESCC) and was treated surgically. Unfortunately, the rhesus monkey was euthanized eventually according to its poor health condition. This provides an important reference for the diagnosis and treatment of ESCC in rhesus monkeys, and also provides an important spontaneous animal model for future research on ESCC.

Indexed as

Carcinoma, Squamous CellEsophageal NeoplasmsEsophageal Squamous Cell CarcinomaMacaca mulattaMonkey DiseasesAnimalsTomography, X-Ray Computedimaging examinationimmunohistochemistryoesophageal squamous cell carcinomarhesus monkey

Identifiers

PMID39950548
PMCPMC11826320

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.