Evidence map›Paper›PMID 39950461›Full record

ArticleCurrent organic synthesis2025

Base Mediated

Rozita Yazzaf, Mina Asadi, Mohammad Mahdavi

Abstract read
PubMed Publisher
In one paragraph

Article in Current organic synthesis, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Multicomponent Reactions for the Synthesis of Oxazepines.Topics in current chemistry (Cham) · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Rozita YazzafSchool of Chemistry, College of Science, University of Tehran, PO Box 14155-6455, Tehran, Iran.
Mina AsadiEndocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.
Mohammad MahdaviEndocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introduction1,4-oxazepine is a significant structural motif found in several bioactive molecules used in the treatment of diseases such as psychotic disorders.

methodsTherefore, developing novel methodologies for its preparation is of great interest to medicinal chemists.

resultsThese seven-membered heterocycles are generated through the intramolecular cyclization of Betti bases, which are propargylated using propargyl bromide as the source of the triple bond in the presence of a base.

conclusionThis efficient and straightforward protocol proceeds under mild, metal-free conditions and has been shown to be applicable to a broad range of aldehydes and 2- aminopyridines.

Indexed as

14-oxazepine7-exo-dig cyclizationbetti reactionbiological activity.multi-component reactionspropargyl bromide

Identifiers

PMID39950461

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.