Evidence map›Paper›PMID 39950459›Full record

ReviewCurrent pharmaceutical design2025

Difficulties in Using Natural Herbal Substances and Their Current use in Some Pharmaceutical Dosage Forms.

Ece Ozcan Bulbul, Neslihan Ustundag Okur

Abstract readReview
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In one paragraph

Review in Current pharmaceutical design, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Ece Ozcan BulbulDepartment of Pharmaceutical Technology, Faculty of Pharmacy, Istinye University, Istanbul, Turkey.ORCID 0000-0001-7112-923X
Neslihan Ustundag OkurDepartment of Pharmaceutical Technology, Faculty of Pharmacy, University of Health Sciences, Istanbul, Turkey.ORCID 0000-0002-3210-3747

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimRandom use of natural herbal products affects the treatment of diseases. In this review, the limitations may be encountered in using natural substances of plant origin and the studies on using these substances in treating cancer, cognitive disorders, heart diseases, diabetes, and microbial diseases are examined and summarized.

backgroundPeople worldwide use herbal products derived from natural plants to solve health problems. It is known that random use of herbal products can negatively affect the treatment. However, people need help with the formulation or use of natural substances. There is no new disease-modifying herbal therapy available to treat diseases such as cancer, microbial disorders, diabetes, cognitive disorders, and cardiac disorders.

objectiveThis review aims to report the difficulties encountered in formulating and using natural herbal substances and highlight their possible use in some diseases. MATERIALS AND

methodsAvailable information about the study was collected through many search engines such as Science Direct, PubMed, and Google Scholar.

resultsWorking with natural herbal substances worldwide presents many difficulties, especially a lack of knowledge, modern technological devices, or clinical studies. According to currently available studies, some natural herbal substances are effective against cancer, microbial disorders, diabetes, cognitive disorders, and heart disorders.

conclusionDeepening the studies would be benefical in eliminating the difficulties related to natural herbal medicines and making them more reliable. More research is needed to include these substances in the protocol and use them in treating diseases.

Indexed as

Biological ProductsDiabetes MellitusNeoplasmsPhytotherapyPlant PreparationsPlants, MedicinalCognition DisordersDosage FormsHeart DiseasesHumansBiological ProductsDosage FormsPlant Preparationscancercardiac disease.cognitive disordersHerbalherbal drugnatural substancepharmaceutical formulationplant

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.