Evidence map›Paper›PMID 39950416›Full record

ArticleVeterinary medicine and science2025

Successful Management of Refractory Otitis Media Using Allergen-Specific Immunotherapy in a Dog.

Jihyun Kim, Ji-Hye Lee, Yeji Kim, Yunji Song, Ha-Jung Kim

Abstract readCase Reports
In one paragraph

Article in Veterinary medicine and science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jihyun KimDepartment of Veterinary Internal Medicine, College of Veterinary Medicine, Chonnam National University, Gwangju, South Korea.
Ji-Hye LeeDepartment of Veterinary Internal Medicine, College of Veterinary Medicine, Chonnam National University, Gwangju, South Korea.
Yeji KimDepartment of Veterinary Internal Medicine, College of Veterinary Medicine, Chonnam National University, Gwangju, South Korea.
Yunji SongDepartment of Veterinary Internal Medicine, College of Veterinary Medicine, Chonnam National University, Gwangju, South Korea.
Ha-Jung KimDepartment of Veterinary Internal Medicine, College of Veterinary Medicine, Chonnam National University, Gwangju, South Korea.ORCID 0000-0002-2699-0263

Funding

Basic Science Research Program through the National Research Foundation of Korea (NRF), funded by the Ministry of Education NRF-2023R1A2C1005348Ministry of Education NRF-2023R1A2C1005348
6 · The paper itself

Abstract

backgroundAllergen-specific immunotherapy (ASIT) is a highly effective treatment for atopic dermatitis. In humans, it has been reported to be significantly more effective than medication alone for the treatment of otitis media. ASIT can also be used in dogs, but it is not typically the first-line treatment for otitis externa and media.

objectivesThis case report describes the successful management of refractory otitis media in a dog with frequent abscess recurrence following total ear canal ablation (TECA) using ASIT.

methodsA 9-year-old spayed female American Cocker Spaniel presented with a head tilt and a recurrent abscess adjacent to the left TECA site. A dermatological examination revealed secondary pyoderma. In open-mouth view radiography and CT, fluid in the tympanic bullae and lysis of the tympanic bullae wall were observed. The TECA was repeated twice and anti-inflammatory medication was administered, but the lesions reappeared. As a fundamental treatment, ASIT was included in the therapy.

resultsAfter ASIT, the symptoms did not reoccur, even though the use of prednisolone was gradually reduced and discontinued over a period of two months. Currently, only ASIT has demonstrated progress in managing the patient's condition, even a year after discontinuing other medications. The patient's symptoms have not recurred and are well managed.

conclusionsA case of refractory otitis media, induced by atopic dermatitis, was effectively managed with ASIT over a prolonged period in a dog.

Indexed as

Desensitization, ImmunologicDog DiseasesOtitis MediaAllergensAnimalsDogsFemaleTreatment OutcomeAllergensallergen‐specific immunotherapyatopic dermatitisdogotitis mediatotal ear canal ablation

Identifiers

PMID39950416
PMCPMC11826327

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.