Evidence map›Paper›PMID 39950361›Full record

ArticleThe Laryngoscope2025

Hearing Loss and Its Relation to Loneliness and Depression-A Population-Based Cohort Study.

Julia Döge, Berit Hackenberg, Manfred E Beutel, Daniëlle Otten, Philipp S Wild, Julian Chalabi, GHS Research Consortium, Christoph Matthias, Katharina Bahr-Hamm

Abstract read
In one paragraph

Article in The Laryngoscope, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Julia DögeDepartment of Otorhinolaryngology, University Medical Center Mainz, Mainz, Germany.ORCID 0000-0002-6998-2992
Berit HackenbergDepartment of Otorhinolaryngology, University Medical Center Mainz, Mainz, Germany.ORCID 0000-0003-4707-1503
Manfred E BeutelDepartment of Psychosomatic Medicine and Psychotherapy, University Medical Center Mainz, Mainz, Germany.
Daniëlle OttenDepartment of Psychosomatic Medicine and Psychotherapy, University Medical Center Mainz, Mainz, Germany.
Philipp S WildCenter for Thrombosis and Hemostasis, University Medical Center Mainz, Mainz, Germany.
Julian ChalabiPreventive Cardiology and Preventive Medicine - Department of Cardiology, University Medical Center Mainz, Mainz, Germany.
GHS Research Consortium
Christoph MatthiasDepartment of Otorhinolaryngology, University Medical Center Mainz, Mainz, Germany.
Katharina Bahr-HammDepartment of Otorhinolaryngology, University Medical Center Mainz, Mainz, Germany.

Funding

Boehringer IngelheimCenter for Translational Vascular Biology, Johannes Gutenberg University of MainzPhilips Medical Systemsresearch program "Wissen schafft Zukunft"Stiftung Rheinland-Pfalz für Innovation
6 · The paper itself

Abstract

objectivesHearing loss is a prevalent factor contributing to reduced quality of life and has been linked to various comorbidities, with potential significant implications for psychosocial and cognitive health. The aim of this study was to give current information about the prevalence of hearing loss, loneliness and depression, and to examine the association between these. STUDY

designCohort study.

methodsThe Gutenberg Health Study, a large representative cohort study for the general population, was initiated in 2007 at the University Medical Center Mainz, Germany. Hearing loss was assessed using pure-tone audiometry, with severity graduated in percentages according to the World Health Organization (WHO). Loneliness and depressive symptoms were assessed using self-report measures: Loneliness Scale (≥2) for loneliness and the PHQ-9 (≥10) for depressive symptoms.

resultsAmong 5,948 participants (25-86 years), the prevalence of hearing loss was 38.7%. Loneliness was reported by 9.5% of the participants and the prevalence of significant symptoms of depression was 9.9%. The risk of loneliness was found to be significantly higher in participants with severe to complete hearing loss (OR = 3.92, p = 0.011). In addition, the odds ratio (OR) for depressive symptoms was significantly higher in those with a mild to severe hearing loss compared to those with normal hearing (OR = 1.3; p = 0.025). There was no association with hearing aid use.

conclusionHearing loss is associated with both loneliness and depressive symptoms. Longitudinal studies are required to clarify the causal relationships and to further investigate the direct impact of early hearing aid fitting on the progression of loneliness and depression. LEVEL OF EVIDENCE: 2 Laryngoscope, 135:2497-2505, 2025.

Indexed as

DepressionHearing LossLonelinessAdultAgedAged, 80 and overAudiometry, Pure-ToneCohort StudiesFemaleGermanyHumansMaleMiddle AgedPrevalenceQuality of LifeSeverity of Illness Indexdepressionhearing aidhearing impairmenthearing lossloneliness

Identifiers

PMID39950361
PMCPMC12230913

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.