ArticleFrontiers in endocrinology2024
Influencing factors of acute kidney injury in elderly patients with diabetic nephropathy and establishment of nomogram model.
Article in Frontiers in endocrinology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1 citing paper in PubMed.
- Identification of Risk Factors and Prediction Models for Acute Kidney Injury in Hospitalized Elderly Patients with Heart Failure.Clinical interventions in aging · 2026Article
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6 authors.
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Abstract
Purpose: To explore the influencing factors of acute kidney injury in elderly patients with diabetic nephropathy and to construct a nomogram model. Methods: The research subjects were 680 patients with type 2 diabetic nephropathy admitted to our hospital. The patients were included from May 2018 to August 2023. Patients with acute kidney injury were used as the merge group (n=50), and patients without unmerge group (n=630) was included. The prevalence and predisposing factors of acute kidney injury in diabetic nephropathy were analyzed, multivariate logistic regression were used to analyze the influencing factors of acute kidney injury in patients, and a nomogram risk prediction model was established based on risk factors for verification. Results: Analysis of the factors of acute kidney injury in diabetic nephropathy found that severe infection was the main trigger, accounting for 40.00%, followed by nephrotoxic antibiotics and severe heart failure. The age, urine microalbumin-to-creatinine ratio (ACR), blood urea nitrogen (BUN), uric acid(UA), and cystatin C (CysC) levels of patients in the combined acute kidney injury group were significantly higher than those in the unmerge group ( Conclusion: The establishment of a nomogram model for acute kidney injury in elderly patients with diabetic nephropathy based on age, ACR, CysC, LVEF, and eGFR has a good predictive effect, which can help doctors more accurately assess the patient's condition and provide a basis for formulating personalized treatment plans.
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