Evidence map›Paper›PMID 39950136›Full record

ArticleFrontiers in tuberculosis2024

Camron M Pearce, Timothy D Shaw, Brendan Podell, Mary Jackson, Marcela Henao-Tamayo, Andres Obregon-Henao, Ha Lam, Ilham M Alshiraihi, Wanda O'Neal, Alessandra Livraghi-Butrico and 3 more

Abstract read
In one paragraph

Article in Frontiers in tuberculosis, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Characterization of new mouse models of acute and chronicAntimicrobial agents and chemotherapy · 2025
    Article
  5. Article
  6. C3HeB/FeJ mice with chronicMycobacteria (London, England) · 2025
    Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Camron M PearceCell and Molecular Biology, Colorado State University, Fort Collins, CO, United States.
Timothy D ShawWellcome-Wolfson Institute for Experimental Medicine, Queen's University Belfast, Belfast, United Kingdom.
Brendan PodellMicrobiology, Immunology and Pathology, Mycobacteria Research Laboratories, NTM Center, Colorado State University, Fort Collins, CO, United States.
Mary JacksonMicrobiology, Immunology and Pathology, Mycobacteria Research Laboratories, NTM Center, Colorado State University, Fort Collins, CO, United States.
Marcela Henao-TamayoMicrobiology, Immunology and Pathology, Mycobacteria Research Laboratories, NTM Center, Colorado State University, Fort Collins, CO, United States.
Andres Obregon-HenaoMicrobiology, Immunology and Pathology, Mycobacteria Research Laboratories, NTM Center, Colorado State University, Fort Collins, CO, United States.
Ha LamMicrobiology, Immunology and Pathology, Mycobacteria Research Laboratories, NTM Center, Colorado State University, Fort Collins, CO, United States.
Ilham M AlshiraihiMicrobiology, Immunology and Pathology, Mycobacteria Research Laboratories, NTM Center, Colorado State University, Fort Collins, CO, United States.
Wanda O'NealMarsico Lung Institute, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States.
Alessandra Livraghi-ButricoMarsico Lung Institute, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States.
Anthony J HickeyRTI International, Research Triangle Park, Durham, NC, United States.
Bernd MeibohmDepartment of Pharmaceutical Sciences, College of Pharmacy, University of Tennessee Health Science Center, Memphis, TN, United States.
Mercedes Gonzalez-JuarreroCell and Molecular Biology, Colorado State University, Fort Collins, CO, United States.

Funding

Inhaled tigecycline therapy for pulmonary M. abscessus infectionsR01AI155922 · NIAID · COLORADO STATE UNIVERSITY · PI GONZALEZ-JUARRERO, MERCEDES, MALONEY, SARA ELIZABETH · 2021 to 2025
$3.6M
Vectra Polaris microscope imaging systemS10OD030263 · OD · COLORADO STATE UNIVERSITY · PI GONZALEZ-JUARRERO, MERCEDES · 2021 to 2021
$452k
NIAID NIH HHS R01 AI155922NIH HHS S10 OD030263
6 · The paper itself

Abstract

Introduction: Chronic pulmonary infection with Methods: Mice received an intrapulmonary aerosol of Results: Endpoint CFU data in the lung and spleen showed that there was no significant difference in bacterial clearance between βENaC and WT mice. WBP data showed an impairment in overall respiratory function during and after Discussion: Even with CF-like features, the βENaC transgenic mice cleared

Indexed as

cystic fibrosismouse modelsMycobacterium abscessusrespiratory functionβENaC-Tg

Identifiers

PMID39950136
PMCPMC11822858

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.