Evidence map›Paper›PMID 39950125›Full record

ArticleFrontiers in medicine2025

Diagnostic value and safety of contact laser-assisted endobronchial ultrasound-guided tunnel drilling biopsy in mediastinal and hilar lymphadenopathy: a retrospective study.

Wenyu Zhan, Tian Wang, Changqing Yang, Yubao Wang, Nansheng Wan, Jing Feng

Abstract read
In one paragraph

Article in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Wenyu Zhan *Respiratory Department, Tianjin Medical University General Hospital, Tianjin, China.
Tian Wang *Respiratory Department, Tianjin Medical University General Hospital, Tianjin, China.
Changqing YangRespiratory Department, Tianjin Medical University General Hospital, Tianjin, China.
Yubao WangRespiratory Department, Tianjin Medical University General Hospital, Tianjin, China.
Nansheng WanRespiratory Department, Tianjin Medical University General Hospital, Tianjin, China.
Jing FengRespiratory Department, Tianjin Medical University General Hospital, Tianjin, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Mediastinal and hilar lymphadenopathies are primarily diagnosed pathologically. Contact laser-assisted endobronchial ultrasound-guided tunnel drilling biopsy (EBUS-TDB), which uses a laser as a tunneling and incision tool, may yield more satisfactory specimens than conventional endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA), thereby improving the diagnostic yield. This study aims to evaluate the diagnostic value and safety of contact laser-assisted EBUS-TDB compared to EBUS-TBNA in the assessment of mediastinal and hilar lymph nodes. Methods: This retrospective study included patients who presented to our hospital between October 2022 and April 2024 with mediastinal or hilar lymph nodes of short diameter ≥ 1 cm on computed tomography (CT) or abnormally increased lymph node metabolism on positron emission tomography (PET)-CT. All patients underwent both EBUS-TBNA and EBUS-TDB procedures successively. Results: Overall, 278 patients were included in the study, and 244 cases were confirmed. The diagnostic rates ( Conclusion: Contact laser-assisted EBUS-TBNB demonstrates superior diagnostic performance compared to EBUS-TBNA for the evaluation of mediastinal or hilar lymph nodes, making it an alternative to EBUS-TBNA for enhanced diagnostic precision.

Indexed as

contact laser-assisted biopsydiagnostic yieldendobronchial ultrasound-guided tunnel drilling biopsylymph node pathologymediastinal lymphadenopathy

Identifiers

PMID39950125
PMCPMC11821499

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.