Evidence map›Paper›PMID 39950051›Full record

ArticleJournal of pediatrics. Clinical practice2024

Social and Communication Development in Infants with Isolated Agenesis of the Corpus Callosum.

Lynn K Paul, Jasmin Turner, Sooyeon Sung, Jed T Elison

Abstract read
In one paragraph

Article in Journal of pediatrics. Clinical practice, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Lynn K PaulDivision of Humanities and Social Sciences, California Institute of Technology, Pasadena, CA.
Jasmin TurnerDivision of Humanities and Social Sciences, California Institute of Technology, Pasadena, CA.
Sooyeon SungDepartment of Pediatrics, Institute of Child Development, Masonic Institute for the Developing Brain, University of Minnesota, Minneapolis, MN.
Jed T ElisonDepartment of Pediatrics, Institute of Child Development, Masonic Institute for the Developing Brain, University of Minnesota, Minneapolis, MN.

Funding

UNC/UMN Baby Connectome ProjectU01MH110274 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI ELISON, JED THOMAS, GILMORE, JOHN HORACE · 2016 to 2019
$4.5M
Parsing early emerging heterogeneity related to autism spectrum disorderR01MH115046 · NIMH · UNIVERSITY OF MINNESOTA · PI ELISON, JED THOMAS, JACOB, SUMA · 2019 to 2023
$3.8M
Infant Brain and Behavioral Signatures of Later Emerging Risk for PsychopathologyR01MH104324 · NIMH · UNIVERSITY OF MINNESOTA · PI ELISON, JED THOMAS · 2014 to 2018
$2.6M
Early Development in Agenesis of the Corpus CallosumR01HD092430 · NICHD · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI PAUL, LYNN KERLIN · 2018 to 2022
$1.4M
NICHD NIH HHS R01 HD092430NIMH NIH HHS R01 MH104324NIMH NIH HHS R01 MH115046NIMH NIH HHS U01 MH110274
6 · The paper itself

Abstract

Objective: To evaluate the development of social behavior, communication, emotion regulation, and repetitive behaviors in infants with congenital malformation of the corpus callosum, specifically those with isolated agenesis of the corpus callosum (ACC), in comparison with infants who are developing typically. Study design: This case-control longitudinal observation study examined parent report of social behavior, social-communication, emotion regulation, and repetitive behavior development in community-ascertained infants (n = 156) and infants with isolated ACC (n = 57) between 12 and 24 months of age. Results: Infants with isolated ACC produced fewer words at 12 ( Conclusions: Existing data suggest heterogeneity in developmental outcomes among individuals with isolated ACC. The current findings fill a gap in knowledge about development in the second year of life. Surveillance of social and communication ability in infants with ACC may be warranted. The role of the corpus callosum in facilitating rapid interhemispheric information processing affects skills beyond the motor system. More work is needed to identify intervention targets for infants and toddlers with ACC.

Indexed as

ACCcorpus callosumdevelopmentinfancysocial-communication

Identifiers

PMID39950051
PMCPMC11824658

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.