Evidence map›Paper›PMID 39950026›Full record

ArticleFrontiers in endocrinology2025

Risk of neonatal SARS-CoV-2 infection: a retrospective cohort study based on infected mothers with gestational diabetes mellitus.

Jing Ni, Yongfei Zheng, Jiaqi Tian, Lin Zhang, Shuyin Duan

Abstract read
In one paragraph

Article in Frontiers in endocrinology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jing NiSchool of Public Health, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan, China.
Yongfei ZhengSchool of Public Health, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan, China.
Jiaqi TianClinical Medical Research Center for Women and Children Diseases, Key Laboratory of Birth Regulation and Control Technology of National Health Commission of China, Shandong Provincial Maternal and Child Health Care Hospital Affiliated to Qingdao University, Jinan, China.
Lin ZhangClinical Medical Research Center for Women and Children Diseases, Key Laboratory of Birth Regulation and Control Technology of National Health Commission of China, Shandong Provincial Maternal and Child Health Care Hospital Affiliated to Qingdao University, Jinan, China.
Shuyin DuanSchool of Public Health, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The COVID-19 pandemic has posed unprecedented challenges to global public health, especially for pregnant women and their offspring. However, little is known about the impact of maternal SARS-CoV-2 infection on neonatal outcomes, particularly in the context of coexisting gestational diabetes mellitus (GDM). Methods: Hospitalized pregnant women with SARS-CoV-2 infection were retrospectively enrolled between November 2022 and January 2023, and matched with pregnant subjects free of SARS-CoV-2 infection based on their propensity scores. All women were tested for SARS-CoV-2 upon admission as part of routine procedures, then divided into groups of pregnant women with SARS-CoV-2 infection and GDM (SARS2+GDM), pregnant women with SARS-CoV-2 infection but without GDM (SARS2+noGDM), and pregnant women without SARS-CoV-2 infection or GDM (Normal group). A logistic regression model was used to study the risk of GDM, perinatal SARS-CoV-2 infection, and their interaction on neonatal SARS-CoV-2 infection. Results: Of 378 pregnant women with SARS-CoV-2 infection, the neonatal infection rate was higher in the GDM group as compared to the SARS-CoV-2 infection only group, but both SARS-CoV-2 infection rates were lower than that of the normal control group. Logistic regression analysis identified an interaction between maternal SARS-CoV-2 infection and GDM on neonatal infection, where maternal SARS-CoV-2 infection (odds ratio [OR] = 0.31, 95%CI: 0.22-0.44) and vaccination for anti-SARS-CoV-2 (OR = 0.70, 95%CI: 0.50-0.98) were associated with lower odds of neonatal infection, while higher pre-pregnancy body mass index (BMI) (OR = 1.06, 95% CI: 1.02-1.10) and GDM (OR = 1.97, 95%CI: 1.21-3.21) were associated with higher odds of neonatal infection. Conclusions: We demonstrate that the coexistence of GDM and perinatal SARS-CoV-2 infection was associated with an increased probability of neonatal SARS-CoV-2 infection.

Indexed as

COVID-19Diabetes, GestationalInfant, Newborn, DiseasesPregnancy Complications, InfectiousAdultFemaleHumansInfant, NewbornInfectious Disease Transmission, VerticalPregnancyPregnancy OutcomeRetrospective StudiesRisk FactorsSARS-CoV-2COVID-19 pandemicgestational diabetes mellitusinfectionneonatal susceptibilitypregnancy

Identifiers

PMID39950026
PMCPMC11822354

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.