Evidence map›Paper›PMID 39950007›Full record

ArticleAntimicrobial stewardship & healthcare epidemiology : ASHE2025

Handshake antimicrobial stewardship for adult surgical patients.

Abby Kosharek, Elizabeth Neuner, Emily Welch, Spenser January, Alice Bewley, Kevin Hsueh, Sena Sayood

Abstract read
In one paragraph

Article in Antimicrobial stewardship & healthcare epidemiology : ASHE, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Abby KosharekDepartment of Pharmacy, Barnes-Jewish Hospital, St. Louis, MO, USA.
Elizabeth NeunerDepartment of Pharmacy, Barnes-Jewish Hospital, St. Louis, MO, USA.
Emily WelchDepartment of Pharmacy, Barnes-Jewish Hospital, St. Louis, MO, USA.
Spenser JanuaryDepartment of Pharmacy, Barnes-Jewish Hospital, St. Louis, MO, USA.
Alice BewleyDivision of Infectious Diseases, Washington University School of Medicine in St. Louis, St. Louis, MO, USA.
Kevin HsuehDivision of Infectious Diseases, Washington University School of Medicine in St. Louis, St. Louis, MO, USA.ORCID https://orcid.org/0000-0002-6606-4491
Sena SayoodDivision of Infectious Diseases, Washington University School of Medicine in St. Louis, St. Louis, MO, USA.ORCID https://orcid.org/0000-0002-1993-0764

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Evaluate the effects of handshake stewardship on adult general surgical units. Design: Retrospective quasi-experimental pre- and post-intervention study. Setting: A total of 1,278 bed academic medical center with a level 1 trauma center in St. Louis, Missouri. Patients: Adults admitted to general surgery units. Intervention: Once weekly handshake antimicrobial stewardship rounds were initiated in January 2022 on adult general surgery units. The handshake stewardship team consisted of an infectious diseases (ID) physician and pharmacist who reviewed charts of patients receiving systemic antimicrobials without a formal ID consult. Antimicrobial recommendations were delivered in person to general surgery teams including trauma, geriatric trauma, and emergency/general surgery. Results: A total of 1,241 charts were reviewed during the post-implementation period with 391 interventions. Seventy-two percent of those interventions were accepted and the acceptance rate improved over the 18-month post-implementation period. Total antimicrobial usage significantly decreased between the pre- and post-implementation period (608 vs 542 d of therapy/1,000 d present, Conclusion: A once-weekly handshake antimicrobial stewardship program was successfully implemented in general surgery units. Antimicrobial use significantly decreased without negatively impacting hospital mortality.

Identifiers

PMID39950007
PMCPMC11822574

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.