Evidence map›Paper›PMID 39949991›Full record

ArticleAIDS research and treatment2025

Neurocognitive Impairment and HIV Treatment Engagement in Men Who Have Sex With Men Living With HIV Who Report Chronic Pain and Substance Use.

Matthew C Sullivan, Megan R Wirtz, Samantha M McKetchnie, Lauren R Gulbicki, S Wade Taylor, Jonathan D Jampel, Nikhil Banerjee, Conall O'Cleirigh

Abstract read
In one paragraph

Article in AIDS research and treatment, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Update on neurological complications of HIV.Current opinion in HIV and AIDS · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Matthew C SullivanDepartment of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts, USA.ORCID https://orcid.org/0000-0002-2528-7787
Megan R WirtzDepartment of Psychology, The Graduate Center, City University of New York, New York, New York, USA.ORCID https://orcid.org/0000-0002-3273-993X
Samantha M McKetchnieDepartment of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts, USA.ORCID https://orcid.org/0000-0001-8004-4430
Lauren R GulbickiDepartment of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts, USA.ORCID https://orcid.org/0000-0002-2836-9665
S Wade TaylorBehavioral Sciences Research Program, The Fenway Institute, Fenway Health, Boston, Massachusetts, USA.ORCID https://orcid.org/0000-0002-2398-6867
Jonathan D JampelDepartment of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts, USA.ORCID https://orcid.org/0000-0003-3679-0764
Nikhil BanerjeeDepartment of Neurology, Vanderbilt University Medical Center, Nashville, Tennessee, USA.ORCID https://orcid.org/0000-0001-7314-7490
Conall O'CleirighDepartment of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts, USA.ORCID https://orcid.org/0000-0002-5639-5043

Funding

Patient-Oriented Substance Use/Smoking Cessation Research in HIV Treatment and PreventionK24DA062568 · NIDA · MASSACHUSETTS GENERAL HOSPITAL · PI Conall Michael O'Cleirigh · 2024 to 2026
$639k
Integrated Behavioral Treatment for Chronic Pain/Drug Use in Older MSM with HIVR21DA038197 · NIDA · MASSACHUSETTS GENERAL HOSPITAL · PI O'CLEIRIGH, CONALL MICHAEL · 2015 to 2016
$389k
NIDA NIH HHS K24 DA062568NIDA NIH HHS R21 DA038197
6 · The paper itself

Abstract

This study explored relationships between neurocognitive impairment (NCI), engagement in HIV care, and functional disability among sexual minority men aged 50 years or older living with HIV, chronic pain, and recent substance use. Sixty-three participants completed cross-sectional assessments including a neurocognitive screening measure, self-reported HIV medication adherence, past-year attendance at HIV-care appointments, and indices of pain and functional impairment. Mean participant age was 57.2 years; most identified as White (55%), followed by Black/African American (42%). On average, participants reported moderate pain; 66.7% met DSM-5 criteria for a substance use disorder. Average Montreal Cognitive Assessment (MoCA) performance reflected mild NCI. Regression analyses indicated an association between poorer MoCA performance and past-year missed HIV-care appointments (

Indexed as

adherencecognitive processingHIVolder personpain

Identifiers

PMID39949991
PMCPMC11824763

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.