Evidence map›Paper›PMID 39949795›Full record

ArticleFrontiers in neurology2025

Enhancing balance and auditory function in bilateral vestibulopathy through otolithic vestibular stimulation: insights from a pilot study on cochlea-vestibular implant efficacy.

Ángel Ramos-de-Miguel, Morgana Sluydts, Juan Carlos Falcón, Raquel Manrique-Huarte, Isaura Rodriguez, Andrzej Zarowski, Maurizio Barbara, Manuel Manrique, Silvia Borkoski, Joan Lorente and 6 more

Abstract read
In one paragraph

Article in Frontiers in neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Ángel Ramos-de-MiguelUnit of Hearing Loss, Department of Otorhinolaryngology, Head and Neck, Complejo Hospitalario Universitario Insular Materno Infantil, Las Palmas of Gran Canaria, Spain.
Morgana SluydtsEuropean Institute for Otorhinolaryngology, GZA Hospitals Antwerp, Wilrijk, Belgium.
Juan Carlos FalcónUnit of Hearing Loss, Department of Otorhinolaryngology, Head and Neck, Complejo Hospitalario Universitario Insular Materno Infantil, Las Palmas of Gran Canaria, Spain.
Raquel Manrique-HuarteDepartment of Otorhinolaryngology, Clinica Universidad de Navarra, Pamplona, Spain.
Isaura RodriguezUnit of Hearing Loss, Department of Otorhinolaryngology, Head and Neck, Complejo Hospitalario Universitario Insular Materno Infantil, Las Palmas of Gran Canaria, Spain.
Andrzej ZarowskiEuropean Institute for Otorhinolaryngology, GZA Hospitals Antwerp, Wilrijk, Belgium.
Maurizio BarbaraDepartment of NESMOS, ENT Clinic, Sapienza University, Rome, Italy.
Manuel ManriqueDepartment of Otorhinolaryngology, Clinica Universidad de Navarra, Pamplona, Spain.
Silvia BorkoskiUnit of Hearing Loss, Department of Otorhinolaryngology, Head and Neck, Complejo Hospitalario Universitario Insular Materno Infantil, Las Palmas of Gran Canaria, Spain.
Joan LorenteDepartment of Otorhinolaryngology, Clinica Universidad de Navarra, Pamplona, Spain.
Marc LeblancEuropean Institute for Otorhinolaryngology, GZA Hospitals Antwerp, Wilrijk, Belgium.
Antonin RambaultCochlear Technology Centre, Mechelen, Belgium.
Erika Van BaelenCochlear Technology Centre, Mechelen, Belgium.
Carl Van HimbeeckCochlear Technology Centre, Mechelen, Belgium.
Alicia HuarteDepartment of Otorhinolaryngology, Clinica Universidad de Navarra, Pamplona, Spain.
Ángel Ramos MacíasUnit of Hearing Loss, Department of Otorhinolaryngology, Head and Neck, Complejo Hospitalario Universitario Insular Materno Infantil, Las Palmas of Gran Canaria, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: This study evaluates cochleovestibular implants (CVI) for improving auditory and vestibular function in patients with bilateral vestibulopathy and severe-to-profound hearing loss. CVI uniquely combines auditory and vestibular stimulation, offering a potential solution for dual impairments in hearing and balance. Methods: Ten patients underwent CVI implantation. Auditory function was assessed with pure-tone audiometry (PTA) and speech recognition at baseline, 3, and 9 months post-implantation. Vestibular function was measured using the Dynamic Gait Index (DGI), Sensory Organization Test (SOT), posturography, and the Dizziness Handicap Inventory (DHI). Placebo-controlled tests verified cochleovestibular stimulation specificity. Results: Auditory outcomes showed PTA improvements from 78 dB HL preoperatively to 34 dB HL at 3 months and 36 dB HL at 9 months, alongside speech recognition gains. Vestibular improvements included significant DGI ( Discussion: CVI effectively restores auditory and vestibular function, with improvements in hearing, balance, and quality of life. Neural plasticity likely supports long-term benefits. Future research should refine device design and stimulation protocols to enhance outcomes further.

Indexed as

balance improvementbilateral vestibular dysfunctioncochleovestibular implantdynamic gait indexotolithic implantsvestibular rehabilitation

Identifiers

PMID39949795
PMCPMC11821918

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.