Evidence map›Paper›PMID 39949733›Full record

ArticleAnimal nutrition (Zhongguo xu mu shou yi xue hui)2025

Integrated transcriptomic hypothalamic-pituitary-ovarian axis network analysis reveals the role of energy availability on egg production in layers.

Jianling Peng, Yong Cui, Haiping Liang, Shenyijun Xu, Linjian Weng, Meng Ru, Ramlat Ali, Qing Wei, Jiming Ruan, Jianzhen Huang

Abstract read
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In one paragraph

Article in Animal nutrition (Zhongguo xu mu shou yi xue hui), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jianling PengCollege of Animal Science and Technology, Jiangxi Agricultural University, Nanchang 330045, China.
Yong CuiCollege of Animal Science and Technology, Jiangxi Agricultural University, Nanchang 330045, China.
Haiping LiangCollege of Animal Science and Technology, Jiangxi Agricultural University, Nanchang 330045, China.
Shenyijun XuAcademy of Pharmacy, Xi'an Jiaotong-Liverpool University, Jiangsu 215123, China.
Linjian WengCollege of Animal Science and Technology, Jiangxi Agricultural University, Nanchang 330045, China.
Meng RuCollege of Animal Science and Technology, Jiangxi Agricultural University, Nanchang 330045, China.
Ramlat AliCollege of Animal Science and Technology, Jiangxi Agricultural University, Nanchang 330045, China.
Qing WeiCollege of Animal Science and Technology, Jiangxi Agricultural University, Nanchang 330045, China.
Jiming RuanCollege of Animal Science and Technology, Jiangxi Agricultural University, Nanchang 330045, China.
Jianzhen HuangCollege of Animal Science and Technology, Jiangxi Agricultural University, Nanchang 330045, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Energy is a crucial component for maintaining egg production in layers. The hypothalamic-pituitary-ovarian (HPO) axis is an energy-sensitive functional axis for follicle development, synthesis, and secretion of reproductive hormones, and plays a key role in modulating sustained ovulation in layers. To investigate the mechanism of integrated network regulation of the HPO axis under energy fluctuation, ninety Hy-line brown layers (265-day-old, 1.92 ± 0.02 kg) were randomly divided into three groups for a 17-day experiment: a control group (Con group) fed ad libitum from days 1 to 17, an energy-deprived group (ED group) that was fed ad libitum from days 1 to 12 and then underwent a fasting period from days 13 to 17 to induce a pause in laying, and a re-fed group (Rf group) that fasted for seven days (specifically, days 1 to 5, day 7, and day 9), had ad libitum access to feed on days 6 and 8, and was continuously fed from days 10 to 17. Each treatment consisted of 10 replicates with 3 birds per replicate. The study found that energy deprivation significantly decreased reproductive performance such as egg laying rate, ovarian index, number of small yellow follicles (SYF), and normal hierarchical follicles (NHIE) (

Indexed as

Egg productionEnergy deprivationHypothalamic-pituitary-ovarian axisLayerRefeedingTranscriptome

Identifiers

PMID39949733
PMCPMC11821414

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.