Evidence map›Paper›PMID 39949729›Full record

ArticleAnimal nutrition (Zhongguo xu mu shou yi xue hui)2025

Folic acid alleviates the negative effects of dexamethasone induced stress on production performance in Hyline Brown laying hens.

Xi Sun, Chaohui Wang, Sijing Li, Xiaoying Liu, Yun Li, Yumeng Wang, Yuxin Niu, Zhouzheng Ren, Xin Yang, Xiaojun Yang and 1 more

Abstract read
In one paragraph

Article in Animal nutrition (Zhongguo xu mu shou yi xue hui), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Xi SunCollege of Animal Science and Technology, Northwest A&F University, Yangling 712100, China.
Chaohui WangCollege of Animal Science and Technology, Northwest A&F University, Yangling 712100, China.
Sijing LiCollege of Animal Science and Technology, Northwest A&F University, Yangling 712100, China.
Xiaoying LiuCollege of Animal Science and Technology, Northwest A&F University, Yangling 712100, China.
Yun LiCollege of Animal Science and Technology, Northwest A&F University, Yangling 712100, China.
Yumeng WangCollege of Animal Science and Technology, Northwest A&F University, Yangling 712100, China.
Yuxin NiuCollege of Animal Science and Technology, Northwest A&F University, Yangling 712100, China.
Zhouzheng RenCollege of Animal Science and Technology, Northwest A&F University, Yangling 712100, China.
Xin YangCollege of Animal Science and Technology, Northwest A&F University, Yangling 712100, China.
Xiaojun YangCollege of Animal Science and Technology, Northwest A&F University, Yangling 712100, China.
Yanli LiuCollege of Animal Science and Technology, Northwest A&F University, Yangling 712100, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Multiple stressors are believed to deteriorate production performance and cause substantial economic losses in commercial poultry farming. Folic acid (FA) is an antioxidant compound that can improve oocyte function and regulate gut microbiota composition. The current study was conducted to investigate the role of FA in alleviating stress and improving production performance. Sixty Hyline Brown laying hens at 21 weeks of age were randomly divided into three groups, with 10 replicates in each group and each replicate containing two chickens. Each group received basic diet and saline injection (Con group), basic diet with dexamethasone (DXM) injection (DXM group), or basic diet supplemented with FA (13 mg/kg in the premix) with DXM injection (FA group). The feeding trial lasted five weeks. Birds in the DXM and FA groups receiving subcutaneous DXM injections at a dosage of 4.50 mg/kg per day during the first seven days of the trial. Results showed that the levels of corticosterone, triglyceride, total cholesterol, and malondialdehyde in serum were significantly increased in the DXM group (

Indexed as

Folic acidGut microbiotaLaying henMulti-stressor

Identifiers

PMID39949729
PMCPMC11821403

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.