Evidence map›Paper›PMID 39949695›Full record

ArticleJournal of oral and maxillofacial pathology : JOMFP

Atypical jaw swelling in children: An unusual clinical spectrum of Langerhans cell histiocytosis.

K Sithara, Usha Balan, Pk Rajeesh Mohammed, Akhila S Stanly

Abstract readCase Reports
In one paragraph

Article in Journal of oral and maxillofacial pathology : JOMFP. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

K SitharaDepartment of Oral Pathology and Microbiology, KMCT Dental College, Mukkam, Calicut, Kerala, India.
Usha BalanDepartment of Oral Pathology and Microbiology, KMCT Dental College, Mukkam, Calicut, Kerala, India.
Pk Rajeesh MohammedDepartment of Oral Pathology and Microbiology, KMCT Dental College, Mukkam, Calicut, Kerala, India.
Akhila S StanlyDepartment of Oral Pathology and Microbiology, KMCT Dental College, Mukkam, Calicut, Kerala, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Langerhans cell histiocytosis (LCH), also called histiocytosis X or eosinophilic granuloma, is a local or systemic unusual clonal proliferative disorder of Langerhans cells. It has a wide spectrum of clinical presentations and can occur in any age group with predominance in children and young adults. This article presents a rare case of LCH in a 2-year-old girl child which was provisionally diagnosed as an infection of the jaw bone of unknown etiology. Correlating the clinical, radiologic, and histologic features with immunohistochemical analysis aided in arriving at a definitive diagnosis of LCH. Oral manifestations being the earliest presentation seen in around 5%-75% of LCH cases emphasize the role of a dentist in the early detection of this lesion. A myriad of clinical spectra due to pathologic infiltration of Langerhans cells into various systems necessitates oral diagnosis to be followed by a full body scan to detect any systemic involvement. Advanced targeted therapies can improve the survival rate and quality of life in patients with LCH.

Indexed as

Atypical jaw swellingCD1 antigenshistiocytosis XLangerhans cell histiocytosis

Identifiers

PMID39949695
PMCPMC11819628

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.