ArticleJournal of oral and maxillofacial pathology : JOMFP
Unveiling the enigma: Navigating extranodal Rosai-Dorfman disease in the maxilla - A teen's journey.
Article in Journal of oral and maxillofacial pathology : JOMFP. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Rosai-Dorfman disease (RDD), a rare histiocytic disorder, typically manifests as widespread lymphadenopathy. We present a unique case of extranodal RDD in a 14-year-old with a solitary maxillary lesion and mild bilateral submandibular lymphadenopathy. Clinical, radiological, and histopathological assessments confirmed RDD, highlighting the importance of a comprehensive approach. Immunohistochemistry, including CD68, CD45, CD 1a, and S100, played a crucial role in diagnosis. Differential diagnoses encompassed Langerhans cell histiocytosis, Erdheim-Chester disease, lymphomas, and histiocytic sarcoma, necessitating meticulous evaluation. Surgical excision was performed due to bone involvement, leading to successful healing in six months. Our case underscores the significance of a multidisciplinary and scientific approach for accurate RDD diagnosis and management, especially in atypical intraoral presentations.
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