Evidence map›Paper›PMID 39949587›Full record

ArticleJournal of clinical tuberculosis and other mycobacterial diseases2025

Tuberculosis and drug resistance in a region of Southern Italy among native and foreign-born populations: A twelve-year province-based study.

Salvatore Rotundo, Salvatore Nisticò, Helen Linda Morrone, Luigia Gallo, Saveria Dodaro, Carmelo Papola, Pasquale Minchella, Giovanni Matera, Francesca Greco, Luigi Principe and 7 more

Abstract readCase Reports
In one paragraph

Article in Journal of clinical tuberculosis and other mycobacterial diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Managing tuberculosis infection among migrants from high-incidence tuberculosis countries: challenges, strategies and recommendations.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Salvatore RotundoDepartment of Medical and Surgical Sciences, "Magna Graecia" University, 88100 Catanzaro, Italy.
Salvatore NisticòClinical Microbiology Unit, "Renato Dulbecco" University Hospital, "Mater Domini" Medical Center, Catanzaro, Italy.
Helen Linda MorroneDepartment of Medical and Surgical Sciences, "Magna Graecia" University, 88100 Catanzaro, Italy.
Luigia GalloClinical Microbiology Unit, "Renato Dulbecco" University Hospital, "Mater Domini" Medical Center, Catanzaro, Italy.
Saveria DodaroMicrobiology and Virology Unit, "Annunziata" Hospital, Cosenza, Italy.
Carmelo PapolaClinical Microbiology and Virology Unit, Great Metropolitan Hospital "Bianchi-Melacrino-Morelli", Reggio Calabria, Italy.
Pasquale MinchellaMicrobiology and Virology Unit, "Renato Dulbecco" University Hospital, "Pugliese-Ciaccio" Medical Center, Catanzaro, Italy.
Giovanni MateraClinical Microbiology Unit, "Renato Dulbecco" University Hospital, "Mater Domini" Medical Center, Catanzaro, Italy.
Francesca GrecoMicrobiology and Virology Unit, "Annunziata" Hospital, Cosenza, Italy.
Luigi PrincipeClinical Microbiology and Virology Unit, Great Metropolitan Hospital "Bianchi-Melacrino-Morelli", Reggio Calabria, Italy.
Lorenzo Antonio SuraceCenter for Travel and Migration Medicine, Provincial Health Authority of Catanzaro, Lamezia Terme, Italy.
Francesco LuciaDepartment of Health Protection and Social Health Services, Sector of Prevention and Public Health, Regional Council of Calabria, Catanzaro, Italy.
Francesca SerapideDepartment of Medical and Surgical Sciences, "Magna Graecia" University, 88100 Catanzaro, Italy.
Alessandro RussoDepartment of Medical and Surgical Sciences, "Magna Graecia" University, 88100 Catanzaro, Italy.
Carlo TortiDepartment of Safety and Bioethics, Catholic University of the Sacred Heart, Rome, Italy.
Enrico Maria TrecarichiDepartment of Medical and Surgical Sciences, "Magna Graecia" University, 88100 Catanzaro, Italy.
Calabria TB group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tuberculosis (TB) remains a significant global health challenge, with the World Health Organization (WHO) aiming for a 95% reduction in TB deaths by 2030. Disparities in TB detection persist, particularly regarding gender, immigration status, and resistance patterns. In Calabria, Italy-a key entry point for migrants from high-TB-incidence regions-TB poses a notable public health risk. This multicenter, retrospective study examines newly diagnosed TB cases in Calabria from 2012 to 2023, focusing on rifampicin-resistant TB (RR-TB). During this period, 800 TB cases were diagnosed, with 270 (33.7 %) in native-born Italians and 530 (66.2 %) in foreign-born individuals, showing significant differences in age (p < 0.001) and gender (p = 0.013). Among 685 patients of this cohort with available HIV status, 24 (3.5 %) were people living with HIV (PLWH), primarily from Africa, and diagnosed at higher rates of RR-TB (p < 0.001). TB cases varied by province, correlating with specific birthplaces. A total of 27 (3.4 %) RR-TB cases were identified, with heightened resistance to multiple drugs. Among these strains, 20 (74.1 %) were isoniazid-resistant (MDR-TB). This study underscores the need for comprehensive TB control strategies, especially regarding co-infection with HIV and the emergence of drug-resistant strains, emphasizing the importance of early detection and tailored management in Southern Italy.

Indexed as

EpidemiologyMDRMigrationPublic healthRifampicinTB/HIV

Identifiers

PMID39949587
PMCPMC11821412

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.