Evidence map›Paper›PMID 39949492›Full record

ReviewCellular and molecular bioengineering2025

Wireless Devices for Optical Brain Stimulation: A Review of Current Developments for Optogenetic Applications in Freely Moving Mice.

Patrícia Silva, Luis Jacinto

Abstract readReview
In one paragraph

Review in Cellular and molecular bioengineering, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Differential Tissue-Coupled Powering for Battery-Free Injectable Electroceuticals.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Patrícia SilvaDepartment of Biomedicine - Experimental Biology Unit, Faculty of Medicine of the University of Porto (FMUP), 4200-319 Porto, Portugal.
Luis JacintoDepartment of Biomedicine - Experimental Biology Unit, Faculty of Medicine of the University of Porto (FMUP), 4200-319 Porto, Portugal.ORCID 0000-0003-3177-1433

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: Optogenetics is an invaluable tool to study brain circuits, but typical systems rely on tethered approaches to deliver light to the brain that hinder natural behavior. With the increasing prevalence of complex behavioral phenotyping in neuroscience experiments, wireless devices for optical stimulation offer great promise to overcome these limitations. Methods: In this work we critically review recent systems engineering and device design approaches to deliver light to the brain with wireless operation for optogenetic experiments. Results: We describe strategies used for wireless control and communication, wireless power transfer, and light delivery to the brain with a focus on device integration for in vivo operation in freely behaving mice. Conclusion: Recent advances in optoelectronic systems, material science, and microtechnology have enabled the design and realization of miniaturized wirelessly-controlled optical stimulators for true untethered experiments in rodent models.

Indexed as

Neural modulationOptoelectronicsOptogeneticsRodent behaviorWireless devices

Identifiers

PMID39949492
PMCPMC11813840

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.