Evidence map›Paper›PMID 39949456›Full record

ArticleCureus2025

Sebaceous Carcinoma as a Presentation of Muir-Torre Syndrome.

Emily Saurborn, Bukola Adeshina, Isabella G Stuart, Shane Cook

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Emily SaurbornDepartment of Dermatology, Marshall University Joan C. Edwards School of Medicine, Huntington, USA.
Bukola AdeshinaDepartment of Dermatology, Marshall University Joan C. Edwards School of Medicine, Huntington, USA.
Isabella G StuartDepartment of Dermatology, Marshall University Joan C. Edwards School of Medicine, Huntington, USA.
Shane CookDepartment of Dermatology, Marshall University Joan C. Edwards School of Medicine, Huntington, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Muir-Torre syndrome (MTS) is a rare, autosomal dominant condition that is within the spectrum of Lynch syndrome (hereditary nonpolyposis colorectal cancer (HNPCC)). Sebaceous adenomas are among the most specific manifestations of MTS. Other malignancies include tumors of the colon, rectum, and genitourinary systems, such as endometrial, ovarian, urothelial, and prostate cancer. Individuals at risk for MTS are identified using the Mayo score, which assesses risk based on family history of Lynch syndrome-associated cancers, personal history of these cancers, and age at diagnosis of a sebaceous adenoma or visceral malignancy. We present a case of a firm, red-yellow papule on the upper extremity, which was revealed by a biopsy to be a sebaceous adenocarcinoma. Immunohistochemistry was significant for the loss of MSH2 and MLH1.

Indexed as

adenomacarcinomaepitheliomagermlineimmunohistochemistrymicrosatellite instabilitymismatch repairmuir-torre syndromesebaceous neoplasms

Identifiers

PMID39949456
PMCPMC11821365

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.