ArticleCureus2025
Isolated Gallbladder Melanoma: A Diagnostic Conundrum of Primary vs. Metastatic Disease.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Melanoma is a malignant proliferation of melanocytes originating from neural crest cells. Gallbladder melanoma is typically reported as a metastatic disease involving the adjacent liver. Thus, isolated gallbladder melanoma must be either a primary tumor originating within the gallbladder without evidence of metastasis or an isolated metastatic lesion from an unknown or regressed primary site. Regardless of its classification as primary or metastatic, isolated gallbladder melanoma is an extremely rare diagnosis. We present a case of incidentally discovered isolated gallbladder melanoma in a resected specimen from a patient undergoing surgery for symptomatic cholelithiasis. An exhaustive workup failed to identify a primary site outside the gallbladder. The case was reviewed at a multidisciplinary tumor board, and the patient was started on immunotherapy. This case report aims to highlight this rare entity, discuss potential management strategies, and contribute to the limited body of literature on the subject.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.