ArticleCureus2025
Achieving Response With Bolus Dosing of Valproate in Electroconvulsive Therapy (ECT)-Induced Mania: A Case Report.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Abstract
Electroconvulsive therapy (ECT) is an effective treatment for various mental illnesses. While it is an excellent modality in treating depression and severe mania, it can also induce mania in certain specific settings. There is so far scarce literature regarding the management of ECT-induced mania with antipsychotics and mood stabilizers, specifically lithium, utilized in different studies. Moreover, there is limited evidence for using valproate for the symptoms. We present a case vignette about managing mania symptoms after ECT by administering a bolus dose of valproate at each session, resulting in progressively improved outcomes.
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