ArticleJournal of pediatrics. Clinical practice2024
Prevalence of Serious Bacterial Infection in Young Infants with Hypothermia with Positive Respiratory Pathogen Testing.
Article in Journal of pediatrics. Clinical practice, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed.
- Etiology of invasive bacterial infections in infants 90 days and younger presenting to the emergency department in a children's hospital in Saudi Arabia.BMC infectious diseases · 2026Article
- Entering the Icy Waters of Viral Testing and Infant Hypothermia.Journal of pediatrics. Clinical practice · 2024Article
- Impact of a Hypothermic Young Infant Clinical Pathway: A Single Site Study.Sage open pediatricsArticle
Corrections and comments
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Authors and funding
19 authors.
Funding
Abstract
Objectives: We sought to compare the prevalence of serious bacterial infections (SBI; urinary tract infection, bacteremia, and/or meningitis) and invasive bacterial infections (IBI; bacteremia and/or meningitis) among infants with hypothermia with positive vs negative respiratory pathogen testing. Study design: We conducted a multicenter retrospective cohort study of infants ≤90 days presenting to an emergency department or directly admitted to a hospital from September 1, 2016, to May 5, 2021, with reported or documented hypothermia (≤36°C). Positive respiratory pathogen testing included positive single or multiplex nucleic acid amplification testing. The primary outcome was prevalence of SBI, defined as positive blood, urine, and/or cerebrospinal fluid culture and antibiotic treatment course; the prevalence of SBI and IBI was compared between infants with positive vs negative respiratory pathogen tests using the χ Results: Respiratory pathogen testing was obtained in 40.6% (446/1098) of infants with hypothermia; of those, 24.9% (111/446) had a positive respiratory pathogen result. Infants with a positive respiratory pathogen result were more often older, ill-appearing at presentation, and evaluated during fall/winter months. The prevalence of SBI in our cohort was 7.4%, and the prevalence of IBI was 4.5%. There were no associations between respiratory pathogen test result and SBI or IBI. Conclusions: Most young infants with hypothermia evaluated did not have respiratory pathogen testing performed. The diagnosis of SBI or IBI was not associated with a positive respiratory pathogen test. Further research is needed to understand the utility of respiratory pathogen testing in risk stratification for infants with hypothermia.
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