Evidence map›Paper›PMID 39949377›Full record

ArticleMental health and physical activity2023

Acute changes in affective valence and perceived distress predict reductions in PTSD symptom severity.

James W Whitworth, Nicholas J SantaBarbara, Sanaz Nosrat, Michelle M Pebole, Bradley G Cripe, Grace McKeon

Abstract read
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Article in Mental health and physical activity, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

James W WhitworthNational Center for PTSD, VA Boston Healthcare System, Boston, MA, USA.
Nicholas J SantaBarbaraBiobehavioral Sciences Department, Teachers College Columbia University, New York, NY, USA.
Sanaz NosratBiobehavioral Sciences Department, Teachers College Columbia University, New York, NY, USA.
Michelle M PeboleThe Translational Research Center for TBI and Stress Disorders (TRACTS), Veterans Affairs Boston Healthcare System, Boston, MA, USA.
Bradley G CripeNational Center for PTSD, VA Boston Healthcare System, Boston, MA, USA.
Grace McKeonSchool of Population Health, University of New South Wales, Sydney, Australia.

Funding

Intramural VA VA999999RRD VA IK2 RX003564
6 · The paper itself

Abstract

There is a growing amount of experimental evidence demonstrating therapeutic chronic effects of exercise (e.g., resistance exercise, running, and walking) on PTSD symptoms. However, it is currently unclear how individuals with PTSD experience exercise within individual exercise sessions (e.g., pleasurable or distressing), and if these acute experiences influence PTSD symptoms over time. PURPOSE: The objective of this study was to examine the acute effects of high intensity resistance exercise on affect, perceived arousal, and distress among individuals who screened positive for PTSD, using a randomized controlled design. Additionally, this study sought to explore longitudinal relations among affect, arousal, distress, and PTSD symptom severity.

methodsThis study analyzed pooled data from two methodologically similar randomized controlled trials (i.e., a pilot and replication study). Participants (n = 52) were randomly assigned to exercise or non-exercise time-matched control. Data were analyzed with a series of longitudinal mixed-effects regression models.

resultsThe analyses suggest that positive affect increased, and distress decreased significantly during exercise sessions, relative to control. Independent of group, increases in positive affect and decreases in distress also significantly predicted decreases in PTSD symptom severity over the course of the study.

conclusionsTaken together, these findings suggest that high intensity resistance exercise is safe for individuals who screen positive for PTSD, pleasurable, and may have a therapeutic impact on trauma survivors. No evidence for symptom exacerbation was found. Future experimental studies are needed to verify these findings and determine if the observed relationships are similar for other exercise modes, durations, and intensities.

Identifiers

PMID39949377
PMCPMC11823288

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.