ArticleAquaculture nutrition2025
Dietary DHA Regulated the Androgen Production in Male Chinese Tongue Sole
Article in Aquaculture nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Intraspecific Physiological Alterations in Phytoplankton Declined the Food Nutritional Quality in Tropical Nutrient-Manipulated Aquatic Mesocosms.Microorganisms · 2026Article
- Effects of Dietary Docosahexaenoic Acid Levels on the Growth, Body Composition, and Health of Liver and Intestine in Juvenile Tiger Puffer (Animals : an open access journal from MDPI · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Long-chain polyunsaturated fatty acids (LC-PUFA) play key roles in sex steroid hormone synthesis in fish. Regarding docosahexaenoic acid (DHA), currently the regulating effects were mostly evaluated in female fish rather than males. This study aimed to investigate the DHA effects on the sex steroid hormone production in male Chinese tongue sole. Three experimental diets were prepared, containing different DHA levels: a control (C) group (5.16% DHA of total fatty acids [TFA]), a low DHA group (DHA-L, 8.93%), and a high DHA group (DHA-H, 16.47%). A 58-day feeding experiment was conducted, and each diet was fed to triplicate tanks of fish. Additionally, an in vitro study with Leydig's cells of this species was conducted to validate the in vivo results. The concentration of testosterone (T) and 11-ketotestosterone (11-KT) in the serum increased with increasing levels of dietary DHA. Dietary DHA significantly upregulated the expression of steroid hormone biosynthetic genes
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.