Evidence map›Paper›PMID 39949354›Full record

ArticleAdvanced materials technologies2023

Wirelessly Actuated Ciliary Airway Stent for Excessive Mucus Transportation.

Yusheng Wang, Saksham Sharma, Fabien Maldonado, Xiaoguang Dong

Abstract read
In one paragraph

Article in Advanced materials technologies, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Soft Artificial Ciliary Brush with Integrated Haptic Feedback for Efficient Airway Mucus Cleaning.Advanced intelligent systems (Weinheim an der Bergstrasse, Germany) · 2026
    Article
  5. Article
  6. Article
  7. Review
  8. Sensory artificial cilia for in situ monitoring of airway physiological properties.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yusheng WangDepartment of Mechanical Engineering, Vanderbilt University, Nashville, TN 37240, USA.
Saksham SharmaDepartment of Mechanical Engineering, Vanderbilt University, Nashville, TN 37240, USA.
Fabien MaldonadoVanderbilt Institute for Surgery and Engineering, Vanderbilt University, Nashville, TN 37240, USA.
Xiaoguang DongDepartment of Mechanical Engineering, Vanderbilt University, Nashville, TN 37240, USA.

Funding

Wirelessly Actuated Ciliary Stent for Minimally Invasive Treatment of Cilia DysfunctionR21EB035200 · NIBIB · VANDERBILT UNIVERSITY · PI Xiaoguang Dong · 2024 to 2026
$617k
NIBIB NIH HHS R21 EB035200
6 · The paper itself

Abstract

Small-scale cilia-like devices that can manipulate fluids in narrow spaces have great potential in microfluidics, biomechanics, biomedical engineering, and other applications. However, prior studies mostly focus on artificial cilia for pumping fluids in lab-on-a-chip microfluidic applications. The design and control of artificial cilia for transporting viscous mucus in confined and tubular structures remain challenging and medical devices such as airway stents with ciliary function are still missing. Herein, a method is reported that enables integrating artificial cilia arrays on 3D curved surfaces and an airway ciliary stent is presented for excessive mucus transportation. The method allows encoding bioinspired non-reciprocal motion and metachronal waves for efficient fluid pumping in tubular structures. The method also introduces a lubricant hydrogel coating layer on artificial cilia inspired by the periciliary layer in airway cilia, which further enhances viscous fluid transportation. It is demonstrated that a novel ciliary airway stent can transport viscous porcine mucus in a lung phantom even faster than the respiratory cilia in a healthy human lung. The methods of designing, integrating, and controlling artificial cilia on 3D curved surfaces thus enable the unprecedented function of removing excessive mucus beyond traditional airway stents for treating various lung diseases in a minimally invasive manner.

Indexed as

airway stentsartificial ciliamagnetic actuationmucus transportation

Identifiers

PMID39949354
PMCPMC11823681

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.