Evidence map›Paper›PMID 39949321›Full record

ArticleEuro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin2025

Detections of rare enterovirus C105 linked to an emerging novel clade, Spain, 2019 to 2024.

Maria Dolores Fernandez-Garcia, Juan Camacho, Francisco Diez-Fuertes, Estrella Ruiz de Pedro, Nerea García-Ibañez, Ana Navascués, Carla Berengua, Pedro Antequera-Rodriguez, Montserrat Ruiz-García, Maria Teresa Pastor-Fajardo and 1 more

Abstract read
In one paragraph

Article in Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Maria Dolores Fernandez-GarciaCentro Nacional de Microbiología, Instituto de Salud Carlos III, Madrid, Spain.
Juan CamachoCentro Nacional de Microbiología, Instituto de Salud Carlos III, Madrid, Spain.
Francisco Diez-FuertesCentro Nacional de Microbiología, Instituto de Salud Carlos III, Madrid, Spain.
Estrella Ruiz de PedroCentro Nacional de Microbiología, Instituto de Salud Carlos III, Madrid, Spain.
Nerea García-IbañezCentro Nacional de Microbiología, Instituto de Salud Carlos III, Madrid, Spain.
Ana NavascuésHospital Universitario de Navarra, Pamplona, Navarra, Spain.
Carla BerenguaHospital Universitario de la Santa Creu i Sant Pau, Barcelona, Spain.
Pedro Antequera-RodriguezHospital General Universitario Morales Meseguer, Murcia, Spain.
Montserrat Ruiz-GarcíaHospital General Universitario de Elche, Alicante, Spain.
Maria Teresa Pastor-FajardoHospital General Universitario de Elche, Alicante, Spain.
María CabrerizoCentro Nacional de Microbiología, Instituto de Salud Carlos III, Madrid, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Enterovirus (EV)-C105 is a rare genotype not previously detected in Spain. Between 2019 and 2024, we detected EV-C105 in respiratory samples of five patients, through routine EV surveillance. Three cases had respiratory illness and two were hospitalised for neurological illness. Four of the five sequenced strains belonged to an emerging clade (C1), defined by four novel nonsynonymous mutations in key antigenic epitopes. We recommend reinforced clinical awareness and EV genomic surveillance, including respiratory samples, even when symptoms are neurological.

Indexed as

Communicable Diseases, EmergingEnterovirusEnterovirus C, HumanEnterovirus InfectionsRespiratory Tract InfectionsAdultFemaleGenome, ViralGenotypeHumansMaleMiddle AgedPhylogenySpainacute flaccid paralysisEnterovirus Cmolecular surveillance

Identifiers

PMID39949321
PMCPMC11914964

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.