Evidence map›Paper›PMID 39949046›Full record

ReviewCell adhesion & migration2025

Brief biology and pathophysiology of Tekt bundles.

Jun Yin, Min Liu, Xiao Wang, Hongming Miao, Wenjuan He, Wei Liu, Zhongying Yu, Qinghua Zhang, Jialian Bai, Yimei Cheng and 1 more

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Cell adhesion & migration, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Jun YinDepartment of Pathophysiology, College of High Altitude Military Medicine, Army Medical University, Chongqing, China.
Min LiuDepartment of Infectious Diseases, Chongqing Public Health Medical Center, Chongqing, China.
Xiao WangDepartment of Pathophysiology, College of High Altitude Military Medicine, Army Medical University, Chongqing, China.
Hongming MiaoDepartment of Pathophysiology, College of High Altitude Military Medicine, Army Medical University, Chongqing, China.
Wenjuan HeDepartment of Pathophysiology, College of High Altitude Military Medicine, Army Medical University, Chongqing, China.
Wei LiuDepartment of Immunology, Army Medical University, Chongqing, China.
Zhongying YuDepartment of Urology, The 909th Hospital, School of Medicine, Xiamen University, Zhangzhou, China.
Qinghua ZhangReproductive Medical Center, Daping Hospital, Army Medical University, Chongqing, China.
Jialian BaiSchool of Artificial Intelligence and Big Data, Chongqing Industry Polytechnic College, Chongqing, China.
Yimei ChengDepartment of Pharmacy, Southwest Hospital, Army Medical University, Chongqing, China.
Bing NiDepartment of Pathophysiology, College of High Altitude Military Medicine, Army Medical University, Chongqing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tektins, a family of microtubule-stabilizing proteins, are critical for cilia and flagella assembly in mammals. They maintain doublet microtubule stability and ciliary/flagellar motility. Loss of Tekt1-5 causes microtubule instability, impaired motility, and diseases like infertility, retinal degeneration, Mainzer-Saldino syndrome, and diabetic nephropathy. Pathophysiological stimuli regulate Tektin expression through transcriptional, posttranscriptional, translational, and posttranslational modifications. This review summarizes the latest findings on Tektin functions and their role in diseases.

Indexed as

Microtubule-Associated ProteinsAnimalsCiliaHumansMicrotubulesMicrotubule-Associated ProteinsCiliaCiliopathiesflagellamicrotubule inner proteinsTekt bundle

Identifiers

PMID39949046
PMCPMC11834534

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.