Trial reportObesity (Silver Spring, Md.)2025
Pretreatment predictors of weight loss in a 12-month behavioral obesity treatment: a signal detection analysis of DIETFITS.
Trial report in Obesity (Silver Spring, Md.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
3 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Attenuation of Adaptive Thermogenesis by a Culinary Dose of Red Pepper During 24-Hour Negative Energy Balance.Nutrition reviews · 2026Pooled it
- Pre-Intervention Predictors of Meeting a 12-Month Walking Goal in Aging Latino/a Adults: A Signal Detection Analysis Approach.Journal of behavioral medicine · 2025Trial
- Adherence to the Alternate Mediterranean Diet and Multidimensional Sleep Health Among US Adults from the 2017-2018 National Health and Nutrition Examination Survey: Exploring Racial/Ethnic Disparities.Journal of the Academy of Nutrition and Dietetics · 2026Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
objectiveThe objective of this study was to identify pretreatment predictors of weight loss in a 12-month behavioral obesity treatment that restricted either fat or carbohydrates.
methodsParticipants were 436 adults with overweight or obesity from the Diet Intervention Examining The Factors Interacting with Treatment Success (DIETFITS) trial. Signal detection analysis was used to identify which combinations of 51 pretreatment demographic, clinical, behavioral, and psychosocial variables, along with diet type (healthy low-fat vs. healthy low-carbohydrate), formed subgroups that varied in proportion of those achieving at least 5% weight loss at 12 months.
resultsOverall, 51% of participants achieved at least 5% weight loss at 12 months, with eight subgroups identified through signal detection. Diet type was not a key factor. Among racial and ethnic minority participants, the best predictors of weight loss were lower levels of emotional eating, less friend discouragement, and presence of metabolic syndrome. Among non-Hispanic White participants, the best predictors were high confidence in participating fully in the intervention, more family encouragement, and lower outcome expectations.
conclusionsWe found that psychosocial and clinical factors, along with race and ethnicity, successfully differentiated subgroups that varied in their 12-month weight loss. Given the heterogeneity in response to behavioral obesity treatment, these results can help generate hypotheses to move intervention science toward a precision medicine approach by matching individuals to their most suitable obesity treatments.
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