Evidence map›Paper›PMID 39948695›Full record

ArticleJournal of natural products2025

Cyclic Peptide Natural Product Inspired Inhibitors of the Free-Living Amoeba

Chenyang Lu, Samantha Nelson, Gabriela Coy, Chris Neumann, Elizabeth I Parkinson, Christopher A Rice

Abstract read
In one paragraph

Article in Journal of natural products, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Analytical applications of gas-phase ion chemistry enabled by mass spectrometry.Analytical methods : advancing methods and applications · 2026
    Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Chenyang LuDepartment of Comparative Pathobiology, College of Veterinary Medicine, Purdue University, West Lafayette, Indiana 47907, United States.ORCID 0009-0003-0355-5626
Samantha NelsonDepartment of Medicinal Chemistry and Molecular Pharmacology, Purdue University, West Lafayette, Indiana 47907, United States.
Gabriela CoyDepartment of Medicinal Chemistry and Molecular Pharmacology, Purdue University, West Lafayette, Indiana 47907, United States.
Chris NeumannDepartment of Chemistry, Purdue University, West Lafayette, Indiana 47907, United States.
Elizabeth I ParkinsonDepartment of Medicinal Chemistry and Molecular Pharmacology, Purdue University, West Lafayette, Indiana 47907, United States.ORCID 0000-0002-3665-5522
Christopher A RiceDepartment of Comparative Pathobiology, College of Veterinary Medicine, Purdue University, West Lafayette, Indiana 47907, United States.ORCID 0000-0003-0672-9604

Funding

Transgenic Mouse Core Facility Shared Resource (TMCF-SR)P30CA023168 · NCI · PURDUE UNIVERSITY WEST LAFAYETTE · PI John Tesmer · 1985 to 2026
$43.4M
Mining Cryptic Biosynthetic Gene Clusters for Novel Bioactive Compounds and BiocatalystsR35GM138002 · NIGMS · PURDUE UNIVERSITY · PI Elizabeth Ivy Parkinson · 2020 to 2026
$2.9M
NCI NIH HHS P30 CA023168NIGMS NIH HHS R35 GM138002
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Balamuthia mandrillarisBiological ProductsPeptides, CyclicHumansMolecular StructureBiological ProductsPeptides, Cyclic

Identifiers

PMID39948695
PMCPMC11877501

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.