Evidence map›Paper›PMID 39948489›Full record

ArticleBMC cancer2025

Effect of perceived stress on psychological distress in hepatocellular carcinoma patients undergoing TACE: the mediating role of experiential avoidance and the moderating role of trait mindfulness.

Zengxia Liu, Min Li, Yong Jia, Lufang Zheng, Li Chen

Abstract read
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Article in BMC cancer, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Zengxia LiuSchool of Nursing, Anhui medical University, Hefei, 230032, China.
Min LiIntervention Department, First Hospital of Jilin University, Changchun, 130021, China.
Yong JiaSchool of Nursing, Jilin University, 965 Xinjiang Street, Changchun, 130021, China.
Lufang ZhengSchool of Nursing, Jilin University, 965 Xinjiang Street, Changchun, 130021, China.
Li ChenSchool of Nursing, Jilin University, 965 Xinjiang Street, Changchun, 130021, China. chen_care@126.com.

Funding

University Natural Science Research Project of Anhui Province 2023AH050583
6 · The paper itself

Abstract

objectiveThe aim of this study was to explore the moderated mediation mechanism of the relationships among perceived stress, psychological distress, experiential avoidance and trait mindfulness of hepatocellular carcinoma (HCC) patients after transarterial chemoembolization (TACE) in China.

methodsThis study utilized a cross-sectional approach to gather data from 458 HCC patients undergoing TACE. Participants completed self-report measures assessing psychological distress, perceived stress, experiential avoidance and trait mindfulness. Mediation and moderation analyses are carried out in SPSS macro PROCESS.

resultsPerceived stress could affect psychological distress and experiential avoidance could mediate this relationship (mediation effect = 0.041, [95%CI=(0.027, 0.056)]). Trait mindfulness played a role as a moderator in the direct and indirect effect of perceived stress on psychological distress.

conclusionOur findings underscore the vital role of experiential avoidance and trait mindfulness to relieve psychological distress, and provide practical implications for mental health intervention programs of HCC patients undergoing TACE.

Indexed as

Carcinoma, HepatocellularChemoembolization, TherapeuticLiver NeoplasmsMindfulnessPsychological DistressStress, PsychologicalAdultAgedAvoidance LearningChinaCross-Sectional StudiesFemaleHumansMaleMiddle AgedExperiential avoidanceHepatocellular carcinoma.Perceived stressPsychological distressTrait mindfulness

Identifiers

PMID39948489
PMCPMC11827311

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.