Evidence map›Paper›PMID 39948458›Full record

ArticleBMC infectious diseases2025

Awareness, willingness, and uptake of pre-exposure prophylaxis (PrEP) among men who have sex with men in Ghana.

Amos Apreku, Chris Guure, Samuel Dery, Alhassan Yakubu, Gamji Rabiu Abu-Ba'are, Stephen Ayisi Addo, Kwasi Torpey

Abstract read
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Article in BMC infectious diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

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3citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

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3 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Amos AprekuDepartment of Population, Family and Reproductive Health, School of Public Health, University of Ghana, Accra, Ghana.
Chris GuureDepartment of Biostatistics, School of Public Health, University of Ghana, Accra, Ghana. cbguure@ug.edu.gh.
Samuel DeryDepartment of Biostatistics, School of Public Health, University of Ghana, Accra, Ghana.
Alhassan YakubuDepartment of Biostatistics, School of Public Health, University of Ghana, Accra, Ghana.
Gamji Rabiu Abu-Ba'areSchool of Nursing, University of Rochester, New York, USA.
Stephen Ayisi AddoNational AIDS/STI Control Programme, Ghana Health Service, Accra, Ghana.
Kwasi TorpeyDepartment of Population, Family and Reproductive Health, School of Public Health, University of Ghana, Accra, Ghana.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHIV prevalence among men who have sex with men (MSM) in Ghana is 18.1% as compared to 1.6% in the general population. Pre-exposure Prophylaxis (PrEP) is recommended by the World Health Organization (WHO) for people who are HIV-negative and at high risk of acquiring HIV. Since PrEP introduction in Ghana in 2020, little is known nationally about the level of awareness, uptake, and willingness to take PrEP among MSM. This study aims to generate estimates on PrEP awareness, uptake and willingness to use among MSM in Ghana.

methodsWe conducted a bio-behavioral survey among MSM aged 18 years and above in all the 10 traditional regions in Ghana from August 2022 to July 2023 using respondent-driven sampling (RDS). RDS-Analyst was used to compute weights based on the participants' network. Data analysis was restricted to MSM who were HIV-negative and sexually active to estimate the prevalence of awareness, willingness, and uptake of PrEP. A multivariable logistic regression model was used to assess the factors influencing these outcomes.

resultsOut of the 3,420 total MSM surveyed, 2,627 were HIV negative and were included in the analysis, Out of which 44.5% (95% CI: 42.0-47.0) were aware of PrEP, 90.4% (95% CI: 88.0-92.3) were willing to take PrEP and 17.8% (95% CI: 16.0 - 19.8) had ever taken PrEP. In the regression analyses, PrEP awareness was 5-fold higher among those who completed tertiary education (aOR: 5.56, 95% CI: 2.87-10.78, p < 0.001) and 4-fold among those who interacted with peer educators (aOR: 3.78, 95% CI: 2.52-5.67, p < 0.001). In terms of uptake, the odds were almost 9 times among those who had experienced forced sex (aOR: 8.88, 95% CI: 1.42-55.47, p = 0.02). MSM aged 25-34 were less willing to take PrEP (aOR:0.21, 95% CI 0.07-0.65, p = 0.006) and PrEP use was also less likely among those who consumed high alcohol (aOR:0.42, 95% CI 0.19-0.92, p = 0.03) and never tested for HIV (aOR: 0.44, 95% CI" 0.25-0.88, p = 0.017).

conclusionIn Ghana, awareness and willingness to take PrEP to prevent HIV is high, but uptake is low. These results highlight the need for interventions to improve the overall uptake of PrEP among MSM in Ghana, especially among those aged 25-34, high alcohol consumers and those who have never screened for HV. Effective implementation of these findings into the national policies can enhance access and encourage PrEP use, ultimately reducing HIV incidence in Ghana among MSM.

Indexed as

Health Knowledge, Attitudes, PracticeHIV InfectionsHomosexuality, MalePatient Acceptance of Health CarePre-Exposure ProphylaxisAdolescentAdultAnti-HIV AgentsGhanaHumansMaleMiddle AgedSurveys and QuestionnairesYoung AdultAnti-HIV AgentsGhanaHIV preventionMSMPre-exposure prophylaxis

Identifiers

PMID39948458
PMCPMC11827451

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LicenceCC BY-NC-ND
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.