ArticleScientific reports2025
A portable and cost-effective system for electronic nucleic acid mass measurement.
Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- PEI-FeBiosensors · 2025Article
- Protecting Firefighters from Carcinogenic Exposure: Emerging Tools for PAH Detection and Decontamination.Biosensors · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This paper presents a low-cost, portable sensing platform for rapid DNA mass measurement, addressing a critical need in life science research. The platform features a novel interdigital open-gate junction field-effect transistor (ID-OGJFET) with a large sensing area that converts negatively charged DNA mass into an electrical current. The system enables DNA mass detection in under ten seconds with a resolution of less than 1 µA, demonstrating sensitivity across a range from 0.48 ng to 29.5 ng, achieving a Limit of Detection as low as 1.18-1.25 ng/µL. A custom-designed electronic reader and fluidic sample holder facilitate efficient operation. Simulation studies using molecular dynamics and finite element methods provide further insights into the sensor's DNA detection mechanism. This highly sensitive system is significantly more cost-effective than commercially available semiconductor characterization alternatives. The device's high performance and affordability make it a valuable tool for molecular biology applications, and it holds potential for advancing FET-based sensing instrumentation and measurement research.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.