Evidence map›Paper›PMID 39948151›Full record

ArticleCommunications biology2025

The proteomic landscape of stool-derived extracellular vesicles in patients with pre-cancerous lesions and colorectal cancer.

Emmalee J Northrop-Albrecht, Yohan Kim, William R Taylor, Shounak Majumder, John B Kisiel, Fabrice Lucien

Abstract read
In one paragraph

Article in Communications biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
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  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Emmalee J Northrop-AlbrechtDivision of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, USA. Northrop.emmalee@mayo.edu.ORCID http://orcid.org/0000-0002-4791-1683
Yohan KimDepartment of Urology, Mayo Clinic, Rochester, MN, USA.
William R TaylorDivision of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, USA.
Shounak MajumderDivision of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, USA.
John B KisielDivision of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, USA.
Fabrice LucienDepartment of Urology, Mayo Clinic, Rochester, MN, USA. Lucien-Matteoni.Fabrice@mayo.edu.ORCID http://orcid.org/0000-0001-6149-345X

Funding

Women's Cancer ProgramP30CA015083 · NCI · MAYO CLINIC ROCHESTER · PI Lila J. Rutten · 1985 to 2026
$151.3M
Minimally Invasive Molecular Approaches for the Detection of Barrett’s Esophagus and Esophageal AdenocarcinomaR01CA241164 · NCI · MAYO CLINIC ROCHESTER · PI Jagpreet Chhatwal, Prasad G. Iyer · 2019 to 2026
$3.9M
Multi-site Gastrointestinal Cancer Detection by Stool DNA MethylationR37CA214679 · NCI · MAYO CLINIC ROCHESTER · PI KISIEL, JOHN · 2018 to 2024
$2.8M
Multi-cancer Early DetectionR01CA214679 · NCI · MAYO CLINIC ROCHESTER · PI John Kisiel, Niloy Jewel Samadder · 2025 to 2026
$891k
NCI NIH HHS P30 CA015083NCI NIH HHS R01 CA214679NCI NIH HHS R01 CA241164NCI NIH HHS R37 CA214679U.S. Department of Health & Human Services | NIH | National Cancer Institute (NCI) CA214679
6 · The paper itself

Abstract

Colorectal cancer (CRC) is the 2

Indexed as

Colorectal NeoplasmsExtracellular VesiclesFecesProteomeProteomicsBiomarkers, TumorFemaleHumansMaleUltrafiltrationBiomarkers, TumorProteome

Identifiers

PMID39948151
PMCPMC11825688

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.