Evidence map›Paper›PMID 39948010›Full record

ArticleResearch in social & administrative pharmacy : RSAP2025

The importance of rigor in pharmacy research: Challenges and solutions.

Michael R Gionfriddo, Chyna McClendon, David A Nolfi, Melissa A Kalarchian, Jordan R Covvey

Erratum issuedAbstract read
In one paragraph

Article in Research in social & administrative pharmacy : RSAP, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Michael R GionfriddoMayo Clinic, Rochester, MN, USA.
Chyna McClendonDuquesne University School of Pharmacy, Pittsburgh, PA, USA.
David A NolfiDuquesne University Gumberg Library, Pittsburgh, PA, USA.
Melissa A KalarchianDuquesne University School of Nursing, Pittsburgh, PA, USA.
Jordan R CovveyDuquesne University School of Pharmacy, Pittsburgh, PA, USA. Electronic address: covveyj@duq.edu.

Funding

Enhancing experimental rigor through education in evidence synthesisUE5NS128228 · NINDS · DUQUESNE UNIVERSITY · PI COVVEY, JORDAN RANDALL, GIONFRIDDO, MICHAEL ROSS · 2022 to 2024
$269k
NINDS NIH HHS UE5 NS128228
6 · The paper itself

Abstract

Scientific rigor broadly refers to upholding basic principles within the conduct of research. Various threats associated with rigor exist in today's research environment, such as the replication crisis, the increasing prevalence of misconduct, and a loss of public trust in regulatory and educational institutions. The purpose of this commentary is to identify problems and solutions associated with research rigor, with a focus on pharmacy research. Problems exist at many levels, including within variable research training/funding, institutional pressures associated with career advancement, and norms associated with academic publishing. However, solutions are possible as methods of harm reduction, including (but not limited to) focused initiatives supporting rigor, team-based approaches to research that include diverse interested parties, and a reimagining of what constitutes value within science. Pharmacists and pharmacy researchers are called upon to uphold research rigor as a professional and ethical responsibility.

Indexed as

Pharmacy ResearchResearch DesignHumansPharmacistsBiomedical researchPeer reviewPharmacy researchReproducibility of resultsResearchResearch design

Identifiers

PMID39948010
PMCPMC11938212

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.