Evidence map›Paper›PMID 39947680›Full record

ArticleBMJ (Clinical research ed.)2025

Uncertainty of risk estimates from clinical prediction models: rationale, challenges, and approaches.

Richard D Riley, Gary S Collins, Laura Kirton, Kym Ie Snell, Joie Ensor, Rebecca Whittle, Paula Dhiman, Maarten van Smeden, Xiaoxuan Liu, Joseph Alderman and 10 more

Abstract read
In one paragraph

Article in BMJ (Clinical research ed.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
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  4. Review
  5. Article
  6. Article
  7. Article
  8. Factors Influencing Physician Adherence to Venous Thromboembolism Risk Assessment Model Recommendations: A Best-Worst Scaling.American journal of cardiovascular drugs : drugs, devices, and other interventions · 2026
    Article
  9. Article
  10. Article
  11. Article
  12. Review
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  14. Article
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  16. Article
  17. Article
  18. Article
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  20. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Richard D RileyDepartment of Applied Health Sciences, School of Health Sciences, College of Medicine and Health, University of Birmingham, Birmingham, UK r.d.riley@bham.ac.uk.ORCID https://orcid.org/0000-0001-8699-0735
Gary S CollinsCentre for Statistics in Medicine, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK.
Laura KirtonCancer Research UK Clinical Trials Unit, School of Medical Sciences, College of Medicine and Health, University of Birmingham, Birmingham, UK.
Kym Ie SnellDepartment of Applied Health Sciences, School of Health Sciences, College of Medicine and Health, University of Birmingham, Birmingham, UK.
Joie EnsorDepartment of Applied Health Sciences, School of Health Sciences, College of Medicine and Health, University of Birmingham, Birmingham, UK.
Rebecca WhittleDepartment of Applied Health Sciences, School of Health Sciences, College of Medicine and Health, University of Birmingham, Birmingham, UK.
Paula DhimanCentre for Statistics in Medicine, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK.
Maarten van SmedenJulius Center for Health Sciences and Primary Care, University Medical Centre Utrecht, Utrecht University, Utrecht, Netherlands.
Xiaoxuan LiuNational Institute for Health and Care Research (NIHR), Birmingham Biomedical Research Centre, Birmingham, UK.
Joseph AldermanNational Institute for Health and Care Research (NIHR), Birmingham Biomedical Research Centre, Birmingham, UK.
Krishnarajah NirantharakumarDepartment of Applied Health Sciences, School of Health Sciences, College of Medicine and Health, University of Birmingham, Birmingham, UK.
Jay Manson-WhittonPeterhouse, Trumpington Street, University of Cambridge, Cambridge, UK.
Andrew J WestwoodBone Cancer Research Trust, Leeds, UK.
Jean-Baptiste CazierFrancis Crick Institute, London, UK.
Karel G M MoonsJulius Center for Health Sciences and Primary Care, University Medical Centre Utrecht, Utrecht University, Utrecht, Netherlands.
Glen P MartinDivision of Informatics, Imaging and Data Science, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester, UK.
Matthew SperrinDivision of Informatics, Imaging and Data Science, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester, UK.
Alastair K DennistonNational Institute for Health and Care Research (NIHR), Birmingham Biomedical Research Centre, Birmingham, UK.
Frank E HarrellDepartment of Biostatistics, Vanderbilt University School of Medicine, Nashville, TN, USA.
Lucinda ArcherDepartment of Applied Health Sciences, School of Health Sciences, College of Medicine and Health, University of Birmingham, Birmingham, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID39947680
PMCPMC12128882

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.