ArticleThe Annals of thoracic surgery2025
Ideal Timing of Coronary Artery Bypass Grafting After Non-ST-Segment Elevation Myocardial Infarction.
Article in The Annals of thoracic surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- The Inverted Circuit: Attribution, Answerability, and Accountability in Canadian Health Governance.The Milbank quarterly · 2026Article
- Reply to Bayici et al.Interdisciplinary cardiovascular and thoracic surgery · 2026Article
- Advances in Diagnosis and Therapeutic Guidance for Acute Coronary Syndrome: A Narrative of A Precision Medicine Approach.Reviews in cardiovascular medicine · 2026Review
- Coronary Artery Bypass Grafting Following ST Elevation Myocardial Infarction Outcomes Are Associated with Time to Surgery.Interdisciplinary cardiovascular and thoracic surgery · 2026Article
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Authors and funding
15 authors.
Funding
Abstract
backgroundPatients with non-ST-segment elevation myocardial infarction (NSTEMI) benefit from revascularization, but guidelines are vague regarding optimal timing. This study aimed to identify the ideal timing of coronary artery bypass grafting (CABG) after NSTEMI.
methodsStudy investigators examined patients with NSTEMI who underwent isolated CABG within 30 days of cardiac catheterization between July 2011 and July 2023 in a multicenter regional collaborative. Patients were stratified into 3 groups: ≤2 days, 3 to 7 days, and 8 to 30 days. Multivariable logistic regression analysis was performed to identify risk factors associated with mortality.
resultsStudy investigators identified 10,271 patients who underwent CABG: 3464 (34%) of these patients underwent CABG within ≤2 days, 5751 (56%) at 3 to 7 days, and 1056 (10%) at 8 to 30 days. The 3- to 7-day group had the lowest median The Society of Thoracic Surgeons predicted risk of mortality (1.36% vs 1.35% vs 2.09%; P < .001). The ≤2-day group more frequently presented with left main coronary artery disease (19% vs 16% vs 16%; P < .001) and cardiogenic shock (5.1% vs 1.8% vs 2%; P < .001). Mean cardiopulmonary bypass time was similar among the groups (97 minutes vs 97 minutes vs 97 minutes; P = .63). The 3- to 7-day group had the lowest operative mortality (3.2% vs 1.8% vs 4%; P < .001) and major morbidity (14% vs 11% vs 16%; P < .001). After risk-adjustment, the 3- to 7-day window was associated with decreased mortality compared with ≤2 days (odds ratio [OR], 0.56; 95% CI, 0.4-0.78; P < .001) and 8 to 30 days (OR, 0.51; 95% CI, 0.32-0.81; P < .001).
conclusionsCABG between 3 and 7 days after cardiac catheterization for NSTEMI was associated with the lowest risk of mortality. When possible, CABG within this window may afford better outcomes.
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