Evidence map›Paper›PMID 39947149›Full record

ArticleFolia phoniatrica et logopaedica : official organ of the International Association of Logopedics and Phoniatrics (IALP)2025

Treatment Effects of Combined Transoral Injection Laryngoplasty with Short Voice Therapy in Patients with Unilateral Vocal Fold Immobility: A Pilot Study.

Silvan Marti, Silvan Marti, Joerg E Bohlender, Meike Brockmann-Bauser

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Folia phoniatrica et logopaedica : official organ of the International Association of Logopedics and Phoniatrics (IALP), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Silvan MartiDivision of Phoniatrics and Speech Pathology, Department of Otorhinolaryngology, Head and Neck Surgery, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
Silvan MartiDivision of Phoniatrics and Speech Pathology, Department of Otorhinolaryngology, Head and Neck Surgery, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
Joerg E BohlenderDivision of Phoniatrics and Speech Pathology, Department of Otorhinolaryngology, Head and Neck Surgery, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
Meike Brockmann-BauserDivision of Phoniatrics and Speech Pathology, Department of Otorhinolaryngology, Head and Neck Surgery, University Hospital Zurich, University of Zurich, Zurich, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionInjection laryngoplasty (IL) in combination with short voice therapy (SVT) has been recommended in unilateral vocal fold immobility (UVFI). This pilot study investigated functional voice changes, age, and time-to-treatment effects in UVFI after transoral IL with hyaluronic acid and SVT.

methodsSeventeen adults with UVFI (mean age: 61 years) were retrospectively analyzed. Outcome measures were the Voice Handicap Index 9i (VHI-9i), perceptual Grading-Roughness-Breathiness-Asthenia-Strain (GRBAS) Scale, voice range profiles (VRP) of the speaking, calling, and singing voice, maximum phonation time, jitter, and the Dysphonia Severity Index (DSI). t tests and Wilcoxon tests evaluated treatment effects; age and time-to-treatment effects on the magnitude of change were assessed by Spearman's correlation.

resultsThere were significant improvements in VHI-9i and GRBAS scale overall grade of dysphonia, roughness, breathiness, and asthenia. Mean speaking and mean calling sound pressure level (SPL), maximum singing SPL, and mean calling fundamental frequency (f

conclusionTransoral IL with SVT significantly improves subjective, perceptual, and instrumental acoustic voice outcomes in UVFI. Improvement of speaking and calling VRP after IL has not been previously documented. Our findings suggest that early treatment is beneficial for mean speaking loudness, maximum singing SPL, singing SPL range, jitter, and the DSI. More research is needed to examine the influence of time-to-treatment and age, and also to what extent SVT contributes to treatment effects.

Indexed as

Hyaluronic AcidLaryngoplastyVocal Cord ParalysisVoice TrainingAdultAgedCombined Modality TherapyDysphoniaFemaleHumansInjectionsMaleMiddle AgedPilot ProjectsRetrospective StudiesTreatment OutcomeHyaluronic AcidGRBAS scaleInjection laryngoplastyInstrumental acoustic measurementsTreatment outcomesUnilateral vocal fold immobility

Identifiers

PMID39947149
PMCPMC12490839

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.