Evidence map›Paper›PMID 39946581›Full record

ArticleBiopsychosocial science and medicine2025

Spirituality and Cardiovascular Health in the HANDLS Study: Evidence for Within-race Differences.

Jason J Ashe, Shari R Waldstein, Rupsha Singh, Christian A Maino Vieytes, May A Beydoun, Nicolle Mode, Alyssa Gamaldo, Marsha Hampton Jarmon, Orfeu Buxton, Michele K Evans and 1 more

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Article in Biopsychosocial science and medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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0 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

11 authors.

Shari R Waldstein
Rupsha Singh
Christian A Maino Vieytes
May A Beydoun
Nicolle Mode
Alyssa Gamaldo
Marsha Hampton Jarmon
Orfeu Buxton
Michele K Evans
Alan B Zonderman

Funding

Healthy Aging In Neighborhoods of Diversity Across the Life Span (HANDLS)ZIAAG000513 · NIA · NATIONAL INSTITUTE ON AGING · PI EVANS, MICHELE K · 2009 to 2025
$70.9M
University of Maryland Claude D. Pepper Older Americans Independence Center (UM-OAIC)P30AG028747 · NIA · UNIVERSITY OF MARYLAND BALTIMORE · PI ALICE S. RYAN · 2006 to 2026
$28.9M
Healthy Aging Neighborhoods of Diversity Across LifespanZ01AG000513 · NIA · NATIONAL INSTITUTE ON AGING · PI EVANS, MICHELE K · 2001 to 2008
$6.8M
Business and regulatory development for Integrating sleep enhancement technology into clinical practiceR44AG056250 · NIA · PROACTIVE LIFE, INC. · PI GARTENBERG, DANIEL · 2020 to 2022
$2.5M
Non-pharmacological improvement of sleep structure in older peopleR43AG056250 · NIA · MOBILE SLEEP TECHNOLOGIES, LLC · PI GARTENBERG, DANIEL, GERASHCHENKO, DMITRY · 2017 to 2018
$696k
Intramural NIH HHS Z01 AG000513Intramural NIH HHS ZIA AG000513NIA NIH HHS P30 AG028747NIA NIH HHS R43 AG056250NIA NIH HHS R44 AG056250
6 · The paper itself

Abstract

objectiveThis cross-sectional study explored the associations between spiritual transcendence (ST)-prayer/meditation fulfillment, connectedness, and universality- and the American Heart Association's Life's Simple 7 (LS7), and if variations across and within racial and socioeconomic groups emerged.

methodsData were taken from the Healthy Aging in Neighborhoods of Diversity across the Life Span study and included 1110 midlife and older African American and white adults [mean (SD) age=56.13 (8.91) y; 65.0% above poverty; 78.1% ≥high school education]. ST was self-reported. LS7 comprised physical activity, smoking, diet, body mass index, cholesterol, glucose, and blood pressure. Higher LS7 reflects better cardiovascular health (CVH). Multiple linear regression estimated associations between ST and LS7. A 3-way interaction term (ST, race, and either education or poverty status) was included in models adjusted for sex and age.

resultsA 3-way interaction was observed for ST, race, and poverty status ( b =1.29, SE=0.35, p <.001). Simple slopes showed a positive association for white adults living above poverty only ( b =0.54, SE=0.15, p <.001). Exploratory analyses found a nonlinear 3-way interactive effect including ST, race, and age (ie, U-shaped; b =0.04, SE=0.02, p =.048). Both lesser and greater ST were associated with higher LS7 for older African American adults exclusively ( b =0.03, SE=0.01, p =.024).

conclusionsAlthough spirituality was associated with overall CVH, it was not beneficial for everyone equally. If tailored appropriately, the integration of spirituality into care practices may promote better CVH. ABBREVIATIONS: AA: African American, AHA: American Heart Association, BMI: body mass index, BP: blood pressure, CVD(s): cardiovascular disease(s), CVH: cardiovascular health, HANDLS: Healthy Aging in Neighborhoods of Diversity across the Life Span, LS7: Life's Simple 7, M: mean, PTSD: posttraumatic stress disorder, SES: socioeconomic status, ST: spiritual transcendence.

Indexed as

Black or African AmericanCardiovascular DiseasesSpiritualityWhiteAgedCross-Sectional StudiesFemaleHealthy AgingHumansMaleMiddle AgedUnited Statescardiovascular healthracial health disparitiessocioeconomic statusspirituality

Identifiers

PMID39946581
PMCPMC12240716

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.